Background: Bloodstream infections caused by Gram-negative bacteria are highly mortal. In this study, we aimed to investigate the relationship between antimicrobial resistance profile and novel serological biomarkers and mortality in bloodstream infections (BSIs) caused by Gram-negative bacteria in ...
It is now well recognized that plasma LPS-binding protein (LBP) and membrane CD14 present at the surface of cells of the myelo/monocytic lineage are central molecules of the innate immune system, in response to LPS or to bacterial products. This paper reviews the ro...
From 2008 to 2010, patients with microbiologically confirmed Gram-negative catheter-related bloodstream infection (GN-CRBSI) were each compared with two randomly selected controls. We included 81 cases (17% of all CRBSI) and 162 controls with CRBSI caused by other pathogens. Incidence of GN-CRBSI...
BMC Infectious Diseases (2019) 19:609 https://doi.org/10.1186/s12879-019-4265-z RESEARCH ARTICLE Open Access Bloodstream infections caused by multidrug-resistant gram-negative bacteria: epidemiological, clinical and microbiological features Helena Ferreira Leal1, Jailton Azevedo1, Giulyana Evelyn ...
Infections caused by Gram-positive bacteria: a review of the global challenge J Infect, 59 (Suppl 1) (2009), pp. S4-S16 View PDFView articleView in ScopusGoogle Scholar 14 S.J. McBride, A. Upton, S.A. Roberts Clinical characteristics and outcomes of patients with vancomycin-susceptible ...
FDA to treat complicated intra-abdominal infections, including those caused by Gram-negative bacteria Gram-negative bacterial infections represent a significant public health threat due to their ability to develop resistan...
Infections caused by a concerning type of antibiotic-resistant bacteria are on the rise in U.S. children, according to a new study published in the Journal of the Pediatric Infectious Diseases Society and available online. Although still uncommon, the ba
New agents for the treatment of infections with Gram-negative bacteria: Restoring the miracle or false dawn? BACKGROUND: Antibiotic resistance in gram-negative resistance has developed without a commensurate response in the successful development of antibiotic age... H Wright,RA Bonomo,DL Paterson -...
Infections due to multidrug-resistant gram-negative bacteria (MDR-GNB) are a significant burden to the healthcare system globally. Colistin is the drug of choice for MDR-GNB and recent studies recommend high doses. This study investigated the safety of low-dose colistin and the relationship of ...
been reported in up to 20% of patients with systemic infections caused by gram- negative bacteria.20 In one study in Brazil, 205 children presented to a hospital with septicemia caused by Staphylococcus aureus (25%), Klebsiella pneumoniae (23%), Pseudomonas aeruginosa (15%), Enterobacter sp. ...