Learn about treatment for UPLIZNA® (inebilizumab-cdon) across all uses, including the support program, on the official patient website. See safety information.
大分子药物研发 | 序列、专利、文献查询平台通过在 智慧芽Bio生物序列数据库——常规搜索中查询Inebilizumab-cdon(伊奈利珠单抗,昕越)重链序列Sequence Code 1191632826,得到如下5000条序列、37000多条专利和1…
作者: 3/13,距离 FDA 批准 Uplizna (inebilizumab-cdon) 治疗 IgG4 相关疾病仅剩数周时间,安进(Amgen)公布了其治疗全身性重症肌无力 (gMG) 的 III 期 MINT 试验的新数据。 抗CD19 抗体是阿斯利康长效 C5 补体抑制剂 Ultomiris (ravulizumab) 和argenx抗 FcRn 抗体 Vyvgart (efgartigimod alfa) 的潜...
Prior to initiating inebilizumab-cdon therapy, test for quantitative serum immunoglobulins.In patients with low serum immunoglobulins, consult an immunology expert before initiating inebilizumab-cdon therapy. Prior to initiating inebilizumab-cdon therapy, evaluate all patients for active or latent tu...
Inebilizumab-cdon(伊奈利珠单抗,昕越)是一种针对CD19的单克隆抗体,主要用于治疗视神经脊髓炎(Neuromyelitis Optica)。该药物通过抑制B淋巴细胞抗原CD19,发挥其药效,作用机制主要包括抗体依赖的细胞毒作用(Antibody-dependent cell-mediated cytotoxicity, ADCC)和B淋巴细胞抗原CD19抑制剂1。该药物由杜克大学原研研发,已...
Uplizna(Inebilizumab-cdon)是一款对CD19具有高度亲和力的人源化单克隆抗体。CD19表达在多类B细胞上,其中包括分泌抗体的成浆细胞(plasmablasts)和浆细胞。通过与CD19抗原结合,Inebilizumab能够迅速将这些细胞从血循环中清除,从而降低自身抗体的产生,缓解患者症状。
Uplizna (inebilizumab-cdon) is proven and medically necessary for the treatment of neuromyelitis optica spectrum disorder (NMOSD) when all of the following criteria are met :Initial Therapy Diagnosis of neuromyelitis optica spectrum disorder (NMOSD) by a neurologist, confirming all of the ...
通过智慧芽Bio生物序列数据库的常规搜索，查询到Inebilizumab-cdon（伊奈利珠单抗，昕越）重链序列Sequence Code 1191632826，共获得5000条序列、37000多条专利和19000多篇文献数据。从图1（交叉引用（序列数））可以看出，共有66条序列同时被专利、文献和其他库公开，没有序列同时被专利和文献公开，1076条...
UPLIZNA® (inebilizumab-cdon) is the first and only FDA-approved CD19+ B-cell-depleting monotherapy proven to reduce attacks in adult AQP4-IgG+ NMOSD patients. See safety info.
Uplizna (inebilizumab-cdon) - Uses, Side Effects, and More Medically Reviewed by Karen Berger, PharmD on Feb 23, 2025 | Written by Patricia Weiser, PharmD Common Brand Name(s): Uplizna Common Generic Name(s): inebilizumab-cdon Pronunciation: up-LIZ-nah, in-EB-i-LIZ-ue-mab Dru...