cancerlocus of controlcopingIndolent and aggressive non-Hodgkin lymphomas (NHL) are common types of hematologic malignancies but their effect on quality of life (QoL) is understudied. In particular, the relation between different aspects of QoL and cognitive impairments and coping styles is relevant ...
and in many, treatment can be deferred for years. However, some patients will have an accelerated course and may experience transformation into aggressive lymphomas
Phase II study of copanlisib, a PI3K inhibitor, in relapsed or refractory, indolent or aggressive lymphoma Ann Oncol (2017) DG Maloney et al. IDEC-C2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma Blood (1997) R Pettengell et...
a (NHL) Patients]]>Kutikova, LucieBowman, LeeChang, StellaLong, Stacey
SM includes indolent to aggressive disease ○ ± multiorgan involvement • Diagnosis of SM requires ○ 1 major and 1 minor criteria, or ○ At least 3 minor criteria • SM usually involves bone marrow ○ Less often: Spleen, lymph nodes, and liver ± skin • Patients with indolent SM ...
Patients with non-Hodgkin lymphoma, who underwent radiotherapy between 1999 and 2016, were identified from the institutional database. We excluded patients with aggressive lymphoma, iNHL stage III and IV, as well as follow up less than 3 months. Patient demographics, tumor characteristic, and compre...
A minority, however, shows a more aggressive course with shorter survival.6 The clinical and biologic features reported as prognostic indicators for splenic MZL are heterogeneous. In some series of patients with non-Hodgkin lymphoma, nodal MZL is a histotype frequently associated with hepatitis C ...
In summary, we describe here the results of whole-genome sequencing of a CLL cohort comprised of low-risk cytogenetic subgroups in which we find that a small subset have complex rearrangements that may be associated with more aggressive disease, while a significant number have only 13q deletion ...
regardless of whether its histology was indolent or aggressive. The log-rank test was used for comparisons of Kaplan-Meier curves for OS and PFS. Cox proportional hazards models were used to determine significant predictors of OS and PFS; Prognostic Factors for DLBCL Patients Undergoing ASCT ...
and are more common with advanced age.3, 4 Indolent B-cell lymphomas, a result of clonal mature B-cell overproliferation, are typically characterized by slow-growth, advanced-stage disease at presentation and a propensity to transform to a more aggressive histological subtype in the terminal ...