Singh Sidhu, J.; Singla, R.; Jaitak, V. Indole Derivatives as Anticancer Agents for Breast Cancer Therapy: A Review. Anti-Cancer Agents Med. Chem. (Formerly Curr. Medi. Chem.-Anti-Cancer Agents) 2016, 16, 160-173. DOI: 10.2174/1871520615666150520144217....
Indole derivatives as anticancer agents United States Patent 8541442 Abstract: The present invention provides compounds of formula (I), their use for the treatment of cancer as well as pharmaceutical compositions comprising said compounds of formula (I)....
- Anti-cancer agents in medicinal chemistry 被引量: 0发表: 2017年 Synthesis of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide as anticancer and anti-inflammatory agents. Thirteen new 2-pyrazoline derivatives bearing benzenesulfonamide moiety (2a-m) were synthesized by ...
EXPLORING 2D AND 3D QSAR STUDIES OF INDOLE/ BENZOXIMIDAZOLE5CARBOXIMIDINE DERIVATIVES AS ANTICANCER AGENTS FOR ... S Agarwal,VK Mishra,V Kumar,... 被引量: 0发表: 0年 Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment Bortezomib is a proteasome inh...
arylthioindole derivatives as anti-cancer compounds in terms of structural requirements needed for drug development. Based on the G-QSAR model, we identified novel therapeutic compounds with improved tubulin assembly inhibition and potent anticancer activities. The compounds were validated for their ...
Beta-carboline-3-carboxamide derivatives as promising antileishmanial agents Ann. Trop. Med. Parasitol., 105 (2011), pp. 549-557 CrossrefView in ScopusGoogle Scholar [23] H. Volpato, lito, V. Desoti, N. Cristina, J. Cogo, M.R. Panice, M.H. Sarragiotto, S.d.O. Silva, T. Ueda...
Indoles are natural organic compounds with an aromatic hetero- cyclic structure that are widely used in the synthesis of pharmaceutical agents. Many synthesized derivatives have potent activity against fungi, viruses and Leishmania parasites as well as Gram-positive and Gram- negative bacteria and ...
The anticancer evaluation, namely the reversion of P-glycoprotein-mediated multidrug resistance, of two sets of monoterpene indole alkaloid derivatives, obtained by modification of some functional groups of two major monoterpene indole alkaloids, is reviewed, as well as the results obtained for a ...
Synthesis of new secretory phospholipase A(2)-inhibitory indole containing isoxazole derivatives as anti-inflammatory and anticancer agents Secretory phospholipase A(2) (sPLA(2)) is an important enzyme that plays a key role in various inflammatory diseases including cancer and its inhibitors ha... ...
The importance of indole and azaindole scaffold in the development of antitumor agentsIndole derivativesAzaindole derivativesAntitumor activityAntiproliferative activityCytotoxicityWith some indoles and azaindoles being successfully developed as anticancer drugs, the design and synthesis of indole and azaindole ...