The invention makes it possible to increase the effectiveness of the release of the indole-3-carbinol from the dosage form and the conversion of same into diindolylmethane, which carries out the demethylating action characteristic thereof.KISELEV, VSEVOLOD IVANOVICH...
Indole-3-carbinol and its derivative diindolymethane (DIM) modulate estrogen metabolism and have anti-carcinogenic, antioxidant and anti-atherogenic properties.
Indole-3-carbinol iNOS: Inducible nitric oxide synthase IRF3: Interferon regulatory factor 3 ITCs: Isothiocyanates Keap 1: Kelch-like ECH-associated protein 1 mRNAs: Messenger RNAs miRNAs: microRNAs MAPK: Mitogen-activated protein kinase AT: N-acetyltransferase NQO1: NADPH:quinone oxidored...
Taiwan Aims: This study investigated the effects of indole-3-carbinol (I3C), a compound from cruciferous vegetables, on various parameters related to obesity, in particular, the parameters of infiltration by macrophages and of inflammatory cytokines expressed during the co-culture of adipocytes and ...
Studies in this laboratory investigated the activities of 1,1-bis(3′-indolyl)methane, a metabolite of the phytochemical indole-3-carbinol as a ligand for the aryl hydrocarbon receptor (AhR) and demonstrated that the addition of a substituted phenyl ring (CDIM) resulted in compounds that bound ...
Indole-3-carbinol, or simply I3C, is a compound that occurs as the byproduct of a natural substance known asglucosinolate glucobrassicin, which is widely available in everyday vegetables andgreenssuch asbroccoli, cauliflower, cabbage, and kale. ...
(2001) Effects of indole-3-carbinol on immune responses, aberrant crypt foci, and colonic crypt cell proliferation in rats. J. Toxicol. Environ. Health, 62, 561-573.Exon JH,South EH,Magnuson BA,Hendrix K.Effects of indole-3-carbinol on immune responses,aberrant crypt foci,and colonic crypt...
0.05-0.15; microcrystalline cellulose 0.5-0.15; magnesium stearate or calcium stearate 0.001-0.004.;EFFECT: invention allows to increase efficiency of release of indole-3-carbinol of dosage form and its conversion into diindolylmethane, which implements its diindolylmethane activity.;1 cl, 3 dwg, 4 ...