Indole-3-aldehyde (I3A) is an intestinal microbial metabolite that regulates inflammation in various inflammatory diseases; however, its role in chronic obstructive pulmonary disease (COPD) remains unclear. This study aimed to investigate the anti-inflammatory effects and molecular mechanisms of I3A in...
中文名称:Indole-3-carbaldehyde 英文名称:Indole-3-carbaldehyde EINECS:207-665-8 中文同义名: 3-吲哚甲醛; 吲哚-3-甲醛; 吲哚-3-甲醛 (3-醛基吲哚); 1H-吲哚-3-甲醛; 3-甲醛吲哚; 吲哚-3-甲醛,99%; 3-醛基吲哚; 英文同义名: INDOL-3-ALDEHYDE; INDOLE-3-ALDEHYDE; INDOLE-3-CARBALDEHYDE; INDOLE...
Indole-3-acetic acid (IAA) and tryptamine (TRA) were found to reduce macrophage production of proinflammatory mediators, such as TNF-α, IL-1β, and monocyte chemoattractant protein 1 (MCP-1), and indole-3-aldehyde (I3A) produced by L. reuteri increases the expression of IL-22 by ILCs...
Indole-3-aldehyde promotes gut barrier function and intestinal epithelial cell proliferation in the small intestine of weaned piglets To investigate the role of IAld, a key tryptophan metabolite from the microbiota, in the intestinal barrier function and development of weaned piglets, we conducted a ...
2018). This produces 3-indolepropionic acid (3-IPA), which binds to the pregnane X receptor (PXR) in intestinal cells. Once absorbed into the bloodstream, IPA is distributed around the body. Another pathway involves Lactobacillus, which metabolizes tryptophan into indole-3-aldehyde (I3A). ...
-3-methanal; 3-Formyl-1H-indole; 3-Formylindole; 3-Indolylformaldehyde; I3CA; INDOL-3-ALDEHYDE; INDOLE-3-ALDEHYDE; INDOLE-3-CARBALDEHYDE; INDOLE-3-CARBOXYALDEHYDE; INDOLE-3-CARBOXYBENZALDEHYDE; Indole-3-carboxylaldehyde; Indole-3-formaldehyde; INDOLYL-3-ALDEHYDE; NSC 10118; β-Indolylaldehyde;...
Indole-3-carboxaldehyde structure CAS No. 487-89-8 Chemical Name: Indole-3-carboxaldehyde Synonyms 1H-INDOLE-3-CARBALDEHYDE;1h-indole-3-carboxaldehyde;3-FORMYLINDOLE;INDOLE-3-ALDEHYDE;INDOLE-3-CARBOXYALDEHYDE;INDOLE-3-CARBALDEHYDE;NSC 269470;INDOL-3-ALDEHYDE;3-Indolealdehyde;Indol-3-carbaldehyde ...
The gut flora can also metabolize dietary tryptophan into indole and its derivatives, such as indole-3-acetic acid (IAA), indoleacrylic acid (IA), indole-3-aldehyde (I3A), and indole-3-propionic acid (IPA). Indole and I3A have been shown to play an important role in maintaining intestina...
Indole-3-carboxaldehyde (3-IAld), a tryptophan metabolite derived from gut microbiota, has been reported to protect the intestine against radiation injury. This study aimed to clarify the role ofBifidobacterium longum(B. longum) and its metabolite indole-3-carboxaldehyde (3-IAld) in the pathophysio...
- The Fischer indole synthesis is a chemical reaction that produces the aromatic heterocycle indole from a (substituted) phenylhydrazine and an aldehyde...- In enzymology, an indole 2,3-dioxygenase (EC 1.13.11.17) is an enzyme that catalyzes the chemical reaction indole + O2 ⇌ {\displaystyle...