To investigate the effect of low-dose, slow-release aspirin in reducing the incidence and/or severity of pregnancy complications in women identified as high risk of developing problems associated with uteroplacental insufficiency, namely pre-eclampsia or delivering a small-for-gestational age (SGA) ...
Initiate within 24 hr of MI and reevaluate for secondary prevention at later date Immediate-release: 60-120 mg/day divided BID/TID; titrate dose based on heart rate and blood pressure as tolerated up to 240 mg/day Supraventricular Arrhythmia Indicated for control of supraventricular arrhythmias...
aspirin 81 mg daily should be given indefinitely after PCI. In patients who are not at high risk of bleeding, a P2Y12 inhibitor should be given daily for at least 6 months
So far, for quite a long time, the use of PDE5i has been shifted away from cardiovascular applications, and it took nearly a decade after sildenafil first clinical introduction to “reallocate” this class of drugs for cardiovascular disorder treatment [48]. As previously stated, PDE5 expressio...
Antiplatelet agents like aspirin and clopidogrel are widely used for indications ranging from primary and secondary prevention of myocardial infarction or ... V Pawan - 《Indian Journal of Urology Iju Journal of the Urological Society of India》 被引量: 36发表: 2009年 First-line treatment for sym...
Monitor for secondary malignancies Heart Failure risk Acute heart failure, often occurring within 1 to 10 days of treatment, has been reported Subclinical decreases in LVEF in up to 50% of cases have also been seen The onset of HF usually resolves over 3 to 4 weeks; However, fatalities cause...
(time to first occurrence of cardiovascular death, myocardial infarction, or stroke; p<0.0001). The results of the primary, key secondary, and other secondary efficacy endpoints in the prespecified testing hierarchy to control for type 1 error are shown in Table 1. The Kaplan-Meier estimates of...
For the last several decades aspirin has been the sole option for antiplatelet therapy in the treatment and prevention of the manifestations of cardiovascular disease. However, a wider selection of antiplatelet agents, including the thienopyridines (ticlopidine and clopidogrel) and the platelet ...
Secondary prevention 100 mg PO once daily or divided q12hr for 6-9 days after myocardial infarction (MI) Alcohol Withdrawal Syndrome (Off-label) 50-100 mg/day PO Supraventricular Arrhythmias (Off-label) Prevention 50 mg/day PO, beginning up to 3 days before surgery and continued until 7 day...
Aspirin and other NSAIDs; unexpectedly severe and fatal GI toxicity can occur with concomitant administration of methotrexate (primarily at high dose) Mercaptopurine Hepatotoxic products Weak acids (eg, salicylates) Nephrotoxic products Nitrous oxide ...