Connective tissue growth factor (CTGF) is overexpressed in diabetic nephropathy (DN) and has therefore been implicated in its pathogenesis. The objective of the present study was to determine the tissue distribution of increased CTGF expression and the relationship of plasma, urinary, and renal CTGF...
Hereby, we assessed the distribution of peripheral Th17 and Treg-cells in patients with undifferentiated connective tissue disease (UCTD), the forerunner of \\{SAIDs\\} and followed these parameters during the development towards definitive SAIDs. Fifty-one \\{UCTD\\} patients were investigated ...
Connective tissue growth factor (CTGF) is overexpressed in diabetic nephropathy (DN) and has therefore been implicated in its pathogenesis. The objective of the present study was to determine the tissue distribution of increased CTGF expression and the relationship of plasma, urinary, and renal CTGF...
Hereby, we assessed the distribution of peripheral Th17 and Treg-cells in patients with undifferentiated connective tissue disease (UCTD), the forerunner of SAIDs and followed these parameters during the development towards definitive SAIDs. Fifty-one UCTD patients were investigated and followed-up for...
Altered Th17 cells and Th17/ regulatory T-cell ratios indicate the subsequent conversion from undif- ferentiated connective tissue disease to definitive systemic autoimmune disorders. Hum Immunol. August 20, 2013. [Epub ahead of print.]Szodoray P,Nakken B,Barath S,et al.Altered Th17 cells ...
Colon cancer evolves from a normal epithelium that functions to provide an extended surface area for the absorption of water and nutrients and excretes mucin in the process. Aiding in these processes are the individual anatomic units collectively known as colonic crypts, comprised of at least 4 ...
Colon cancer evolves from a normal epithelium that functions to provide an extended surface area for the absorption of water and nutrients and excretes mucin in the process. Aiding in these processes are the individual anatomic units collectively known as colonic crypts, comprised of at least 4 ...
However, the organoids only contained the transformed epithelial tumor cells and not the connective tissue, immune or vessel elements. Drug screens were performed on the organoids and IC50 values were reported for cisplatin and carboplatin, showing differential sensitivity of the organoids to these ...