Although not normally present on plasma cells, it is expressed on plasma cells in 70% to 80% of MM cases103 and is also found in certain solid tumors such as neuroblastoma and small-cell lung cancer. Lorvotuzumab mertansine (IMGN901) consists of an anti-CD56 mAb conjugated to a ...
As Entity B was formed by Entity A itself as a subsidiary, Entity A's control of Entity B does not arise from a 'business combination' within the meaning of this term under Ind AS 103,Business Combinations. Consequently, the option available to a first-time adopter...
1. We have a situation where standard says that an entity will have power over other entity when it has current ability (refer Para 10 above) to direct the "relevant activities" (as defined inInd-As 103-"Business Combinations") of an investee which essentially means that existing rights whi...
said, "As one of the first companies to conduct research on CAR-T to treat autoimmune diseases worldwide, our BCMA CAR T-cell therapy represents a significant milestone for Investigator Initiated Trial (IIT) data of relapsed and refractory NMOSD, an autoimmune disease with serious...
“The use of CAR-T cell products has been widely accepted in the treatment of hematologic malignancy but has been rarely reported in the treatment of autoimmune diseases. As one of the first company to use CAR-T cell to treat a...
Center for Drug Evaluation and Research (CDER) Center for Biologics Evaluation and Research (CBER) Oncology Center of Excellence (OCE) October 2019 Electronic Submissions RELATED DOCUMENTS Technical specifications associated with this guidance are provided as separate documents and are updated periodically....
The command output was updated to show SRTP Rollover Count (ROC) information based on Remote IP address and Port. Usage Guidelines This command displays information about RTP named event packets, such as caller ID number, IP address, and port for both the local and remote endpoints. The output...
Unlike most protective agents, LGM2605 works via multiple pathways; these, as we have reported elsewhere, involve scavenging ROS/oxidants but also boosting endogenous antioxidant defenses via Nrf2 signaling as well as by blocking myeloperoxidase activity. Therefore, evaluation of LGM2605 s protective ...
The information that is received from branch offices isn't updated and is kept as it was originally received from the branches. In Finance, changes can't be made to posted financial data. Therefore, financial transactions can't be edited after they are posted. However, they...
Tuple: Updated state after observation """ node_state = state[action.query] assert isinstance( node_state, Normal ), "only Normal distributions are supported as of now" tau_old = 1 / (node_state.sigma**2) # Simulate ground truth sim_ground_truth = sample(self.init[action.query]) # ...