Researchers have also reported that skin-to-skin contact may have analgesic effects on human infants undergoing minor medical procedures [13] and therapeutic effects, reducing pain in patients with cancer or chronic pain [14]. Lack of interpersonal touch or physical neglect can lead to a higher ...
Palmar mechanical sensitivity, cold temperature avoidance and spontaneous behavioral changes increased, while grip strength declined, in 18-week HRHF rats, compared to controls. Flexor digitorum muscles had increased MCP-1 levels after training and increased TNFalpha in 6-week HRHF rats. Serum had ...
defined as reduced food intake without malnutrition, and linked an overall metabolic shift to FAO.22Previously, DR-like phenotypes including improved insulin sensitivity and increased oxidative stress resistance have been observed
Autophagy is an important cellular degradation pathway with a central role in metabolism as well as basic quality control, two processes inextricably linked to ageing. A decrease in autophagy is associated with increasing age, yet it is unknown if this i
Inflammation is interrelated to oxidative stress in CKD [30]. Systemic inflammation is independently associated with increased mortality among pre-dialysis and dialysis CKD patients [31]. High sensitivity CRP has been shown to independently predict mortality in CKD patients [30]. FGF23 and vascular ...
grow ing from the edge of the bovine skin were trypsinized one w eek later, culture d fo r 1 - 2 p assag e s a nd c ry o preserv ed . Hig hly confl ue nt fi brobla st ce lls we re chose n a s d on or cel ls, tre ated w ith 3 m g /m L prona se fo r 5...
However, only RBPMSA expression levels were associated with the sensitivity of ovarian cancer cells to cisplatin treatment. Keywords: RNA Binding Protein with Multiple Splicing; cisplatin resistance; RBPMS variants; ovarian cancer; RBPMS1. Introduction Ovarian cancer is the most lethal gynecologic ...
[30]. This tool consisted of a circular platform with an area of 1 cm2area, which was perpendicularly applied to generate progressive pressure on the skin at a 1 kg/sec rate. Subjects were required to indicate the PPT when the mechanosensitivity stimulus felt uncomfortable or painful. Neutral...
Patients who have undergone surgery in early life may be at elevated risk for suffering neuropathic pain in later life. The risk factors for this susceptibility are not fully understood. Here, we used a mouse chronic pain model to test the hypothesis that early exposure to the general anesthetic...
Given the comprehensive adjustment for numerous covariates, including the most common cause of hypercalcemia (i.e., hyperparathyroidism) in our analyses, the observed association might be explained by genetic factors, resulting in a higher sensitivity of the calcium metabolism to vitamin D and calcium...