Research Indicates No Increased Cancer Risk At Greenock Factory, Scotland
b Red blood cell (RBC) count at days 1–7 post PHZ treatment (n = 3 for day 1 and n = 5 for others). c–e Labeling frequencies of different hematopoietic lineages in the bone marrow and peripheral blood (c, d) or in the spleen (e) of PHZ-treated (blue bars) or ...
indicates presumed maternal inheritance based on pedigree.P value is the result of a two-sided Wilcoxon rank-sum test on total counts of mutations attributed to SBS10a, SBS10b and SBS28.d, Early embryonic insertions of T at homopolymers of T (indicative ofPOLD1mutagenesis) in individuals w...
We defined our normalized chromatin score Si,j as the residual of the regression, corresponding toSi,j=Mi,j−Mi,jˆ,where Mi,jˆ indicates the best fit of the multivariate regression model. We found the residuals were normally distributed, indicating that the linear model adequately fit ...
heterozygote for the c.525_526insCGGCGCC (p.(Gly176Argf- sTer179)) frameshift and c.152T4G (p.(Leu51Arg)) missense muta- tions in the KLF1 gene.16 This indicates that an asymptomatic phenotype likely results from a single c.525_526insCGGCGCC (p.(Gly176ArgfsTer179)) mutation rather...
(single alive) CD8+T cells next to the UMAP with all identified clusters.bDot plot showing the five most differentially expressed genes per cluster. Size of each dot indicates percentage of gene-expressing cells per cluster; color indicates scaled average fold expression of the corresponding gene ...
(per year) versus SBS rate (per year); the cross indicates the SBS and ID rate in normal individuals.f, ID and SBS burden in adenomatous samples from individuals withPOLE/POLD1mutations. The gray box indicates the range of mutation burdens in normal intestinal crypts from individuals with...
Article Increased Circulating Epithelial Tumor Cells (CETC/CTC) over the Course of Adjuvant Radiotherapy Is a Predictor of Less Favorable Outcome in Patients with Early-Stage Breast Cancer Matthias Mäurer 1,2,* , Dorothea Schott 3, Monika Pizon 3 , Sonia Drozdz 1, Thomas Wendt 1, Andrea ...