? Significantly increased estrogen level was only in overweight and obese men >60years. ? Increased estrogen level was associated with depressive symptomatology regardless of BMI in younger men. Abstract Background Several studies have shown a positive association between depression and obesity; however ...
Sex steroids, such as estrogens and androgens, are important regulators of the humoral immune response. Studies in female mice have demonstrated that alteration of circulating estrogen concentration regulates antibody-mediated immunity. As males have nor
Local sex ratios can alter the threat of sexual competition, to which males respond via plastic... I Mohorianu,A Bretman,D Smith,... - 《Rna-a Publication of the Rna Society》 被引量: 0发表: 2017年 Involvement of Estrogen Receptor Alfa in the Development of Immune Response to Syngenic...
Therefore, we hypothesized that ERbeta mediates estrogen-induced cardioprotection through PI3K/Akt and antiapoptotic signaling in females but not in males. Isolated male and female hearts from ERbeta knockout (ERbetaKO) and wild-type (WT) mice (n = 5 mice/group) were subjected to 20-min ...
Estrogen up-regulates Bcl-2 and blocks tolerance induction of nave B cells Sex hormones are presumed to contribute to sexual dimorphism in the immune system. Estrogen, in particular, has been suggested to predispose women to syste... MS Bynoe,CM Grimaldi,B Diamond - 《Proceedings of the Natio...
The prenatally stressed males showed low levels of male copulatory behavior and high rates... IL Ward - 《Origins of Madness》 被引量: 948发表: 1972年 Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator... Discusses the results of a study investigating the ...
Published data suggests that gender differences in susceptibility to SARS-COV (Severe Acute Respiratory Syndrome Coronavirus) in mice were secondary to estrogen receptor signaling, which seemed to be critical for protection in females [12]. However, the role of sex hormones in the regulation of ...
Testing in mice showed ghrelin levels rising in male mice exposed to UVB radiation. Secretion of the hormone was also discovered in skin samples obtained by male human volunteers who were exposed to UV light in the lab. "In females, estrogen interferes with the p53–chromatin interaction on the...
Insulin release in response to a glucose challenge was blunted in conjunction with a reduction in protein expression of pancreatic glucose transporter type 2 and estrogen receptor-α at 12 mo of age in female growth-restricted rats (P < 0.05). Conclusion: This study demonstrated that slow fetal...
12 h) with 2% charcoal/dextran-treated FBS and 1% penicillin/streptomycin in DMEM/F12 at 37 °C. ICI182780 (V900926, Sigma, St. Louis, MO, USA) and mifepristone (M8046, Sigma, St. Louis, MO, USA) were used at a concentration of 1 μM for 24 h to block estrogen recepto...