controlled trial that directly compared differences incalorie consumptionandweight gainbetween an ultra-processed and an unprocessed diet. The team found that even when the two diets were matched for the amount of presented carbohydrates, fat, sugar, salt, and calories, people consumed morefood...
Also, other interventions that increase lifespan, such as calorie restriction and growth hormone receptor knock-out (GHRKO), result in increased mitochondrial activity and/or PGC-1α expression in muscle and liver, respectively27. Moreover, insulin being an anabolic hormone that promotes energy ...
The HFD + NCT mice were markedly less obese (Fig.1F), with substantially less subcutaneous fat (Fig.1N) but no change in epididymal fat pad weight at the end of the study (Fig.1L, M). HFD + NCT mice had redder livers (Fig.1G), and lower liver weight (Fig.1H). Consiste...
Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice Article Open access 11 March 2021 A natural Nrf2 activator glucoraphanin improves hepatic steatosis in high-fat diet-induced obese male mice associated wi...
induce some of this phenotype. We just don't know," Stansfield said, noting that's one of many areas that need more study. Small babies tend to have higher insulin sensitivity so when they are fed a calorie-dense diet, the insulin sensitivity may lead to more efficient fat storage, he ...
Gut microbiota-bile acid crosstalk contributes to the rebound weight gain after calorie restriction in mice ArticleOpen access19 April 2022 Introduction Obesity is a complex disease associated with numerous comorbidities, including metabolic syndrome and cardiovascular diseases1. These pathologies are commonly...
induce some of this phenotype. We just don't know," Stansfield said, noting that's one of many areas that need more study. Small babies tend to have higher insulin sensitivity so when they are fed a calorie-dense diet, the insulin sensitivity may lead to more efficient fat storage, he ...
The biological optimal range is approximately 1% to 2%, but current LA consumption is over 25% of the total calorie intake for the average person [34]. The consumption of LA at these levels lowers the metabolic rate [35,36] and increases tissue oxidative damage that increases susceptibility ...
Lack of physical activity, individual behavior, and food choices drastically influence daily calorie intake. Furthermore, in addition to caloric intake, we must also focus on food quality: due to technological progress in food production processes, there has been a strong reduction in the consumption...