There is an increased concern that statins may have an unintended effect of elevated lipoprotein(a) [Lp(a)]. We conducted a large sample real-world study to test the association. This retrospective cohort study was conducted using data from an integrated
[Updated for projected 2024 Increase]Soaring inflation and related Fed rate hiking actions had a silver lining for many eligible recipients in 2023, with a8.7% increase(~$145 p/month) in Social Security (SS) benefits and Supplemental Security Income (SSI) payments in...
The effect of remnant-cholesterol (remnant-C) on incident end-stage renal disease (ESRD) has not been studied longitudinally. This retrospective cohort study evaluated the association between remnant-C and the development of ESRD in a nationwide Korean c
VOR was found to be the dominant influencer of hurricane activity in the month of September, with r2 value of 0.47. Wavelet local multiple correlation technique showed correlation values to be higher (~ 0.75) for a SSTDIFF鈥揌C pair for the months of August and October. However, VOR鈥揌C...
Recurrent GBMs are not always biopsied, not to mention the difficulty in acquiring omics data from both paired P-R GBM samples. For example, regarding the RNA-seq data of GBM patients in the Cancer Genome Atlas (TCGA; http://cancergenome.nih.gov/), less than 8% of samples are derived...
Invasive growth is a critical process in tumor progression, requiring the activation of various molecular processes in tumor cells at the invasive front. Intercellular communication between heterogeneous tumor cells enhances cellular activation and adapt
Lipopolysaccharide (LPS) is an endotoxin that can cause an acute inflammatory response. Nitric oxide (NO) is one of the most important innate immune system components and is synthesized by inducible NOS (iNOS) in macrophages in response to stimulation wi
2023;6(4):e2311004. doi:10.1001/jamanetworkopen.2023.11004 Key Points Question What is the comparative effectiveness of 2 tailored interventions delivered remotely compared with usual care for increasing any or all needed cancer screenings in rural women? Findings In this randomized clinical trial of...
Supplementation of aspartate or malate increased renal levels of L-arginine and NO and attenuated hypertension in SS rats. These findings reveal a multi-step metabolic pathway important for hypertension in which malate and aspartate may modulate blood pressure by altering levels of L-arginine and NO...
In the surface layer, however, the ongoing deoxygenation will largely stop once CO2 emissions are stopped. Accounting for the joint effects of committed oxygen loss and ocean warming, metabolic viability representative for marine animals declines by up to 25% over large regions of the deep ocean,...