Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease. Neurobiol Aging. 2014 Oct;35(10):2302-15.Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson’s disease[J] . Falk Schlaudraff,Jan ...
Contralateral Retinal Dopamine Decrease and Melatonin Increase in Progression of Hemiparkinsonium Rat 来自 Semantic Scholar 喜欢 0 阅读量: 46 作者:M Tao,ZH Zheng,TT Liu,L Lin 摘要: Abstract 关键词:Parkinson’s disease Retina Dopamine Melatonin ...
aLevodopa is a dopamine precursor which, once it crosses the blood-brain barrier, is converted to dopamine (dopamine cannot cross the bloodbrain barrier). Levodopa is used as a prodrug to increase dopamine levels, most commonly in the treatment of Parkinson’s disease. Levodopa may also improve...
Considering the promising anti-aging activity of magnolol, we further explored its roles in Parkinson’s disease (PD) and Alzheimer’s disease (AD) models ofC. elegans. Age-related loss of dopaminergic neurons is an important feature of PD. There are 8 dopaminergic neurons in nematodes, includin...
Deep brain stimulation (DBS) of the anterior nucleus of the thalamus is an efficacious treatment option for patients with refractory epilepsy. Our previous
Background Current evidence connects impulse control disorders (ICDs) to dopaminergic replacement therapy used for the treatment of Parkinson's disease (PD). Common ICDs include hypersexuality, pathological gambling, compulsive shopping and binge eating. The underlying neuropathology is thought to be due...
In some embodiments the means and methods involve a GUCY2C agonist. The invention also relates to test systems and cells that are suited to identify new candidate compounds for the treatment of Parkinson's disease.VAN DER HEIDE, LARS PHILIP...
In some embodiments the means and methods involve a GUCY2C agonist. The invention also relates to test systems and cells that are suited to identify new candidate compounds for the treatment of Parkinson's disease.VAN DER HEIDE, LARS PHILIP...
BACKGROUND: Current evidence connects impulse control disorders (ICDs) to dopaminergic replacement therapy used for the treatment of Parkinson's disease (PD). Common ICDs include hypersexuality, pathological gambling, compulsive shopping and binge eating. The underlying neuropathology is thought to be ...
Parkinson’s diseaseDA-depletionStriatumRatDopaminergic neuron degeneration is known to give rise to dendrite injury and spine loss of striatal neurons, however, changes of intrastriatal glutamatergic terminals and their synapses after...doi:10.1007/s11064-019-02739-yZheng, Xuefeng...