Among the 5 related events, 3 were reported as myalgia and 2 as increased creatinine levels. There were no serious adverse events reported in the trial. Discussion In this cluster randomized clinical trial among 28 primary care practices, clinician nudges alone and combined with patient nudges ...
The mean between-group differences (hydration vs control) in secondary outcomes were as follows: plasma copeptin, −2.2 pmol/L (95% CI, −3.9 to −0.5; P = .01); creatinine clearance, 3.6 mL/min/1.73 m2 (95% CI, 0.8 to 6.4; P = .01); urine albumin, 7 mg per ...
eGFR was estimated from outpatient serum creatinine concentration using the four-variable Modification of Diet in Renal Disease formula; the date of first eGFR <60 cm3/min per 1.73 m2 was termed the ‘incident CKD date’. The date of the first outpatient Hb <12 g/dl on or after the index...