The results are consistent with the hypothesis that colchicine or its derivatives (colcemide) exert their antimitotic action by reversible oxidation of thiolic proteins present in the cell. This hypothesis could also explain the lack of antimitotic action of thiocol-chisode.doi:10.1080/...
Sul meccanismo di azione della streptomicinaA study was undertaken on the variations of the redox potential level produced by streptomycin in vitro and in vivo . We have been able to show that, owing to an oxidative effect, streptomycin produces an increase of the redox potential level. This...