INA03 is an antibody drug conjugate (ADC) constituted of a humanized monoclonal IgG4against CD71 and the microtubule disrupting agent monomethyl auristatin E (MMAE). We herein report the preliminary safety and efficacy data of INA03 from a phase 1/2 trial in patients (pts) with R/R AL (...
Hafskjold Nrstadc,... - 《Plant Pathology》 被引量: 216发表: 2000年 Hypotheses for the inter-regional movement of new genotypes of Phytophthora infestans in Canada During late blight surveys conducted from 1994 to 1996, hypotheses were developed to explain the migration of novel genotypes of ...
PURPOSE: We provide guidelines of penile length and circumference to assist in counseling patients considering penile augmentation. MATERIALS AND METHODS: We prospectively measured flaccid and erect penile dimensions in 80 physically normal men before and after pharmacological erection. RESULTS: Mean flaccid...
Because infection of macrophages and microglial cells by NSI HIV-1 is considered to be instrumental for the development of AIDS dementia complex (ADC), ... van Rij Ronald P.,P Peter,H Teysir,... - 《Journal of Infectious Diseases》 被引量: 140发表: 1999年 加载更多来源...
Analysis of Zn and Cd in Greenland Holocene ice dated from 7760 to 471 yr ago shows no significant changes during the Greek, Roman and medieval times. It indicates that emissions from early mining and smelting operations were not intense enough for these two metals to have left detectable sign...
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In a recent multicentre, randomised, controlled, open-label study (Rougier and colleagues, Lancet 1998, 352, 1407-1412), irinotecan significantly increased survival without any deterioration in quality of life compared with best-estimated infusional 5-fluorouracil (5-FU) therapy in the setting of se...
The article features Pure Kauai and sister company Pure Maui, which were established by chief executive officer (CEO) Phil Jones to offer an ultimate and customized vacation experience. Pure Kauai also offers luxury accommodations and activities such as yoga, hiking and meditation sessions to individu...
A基金管理公司拟申请登记私募基金管理人,存在( )情形的,协会将不予登记。Ⅰ.为了提高效率,A基金管理公司在申请登记前面向公众发行了一只私募股权投资基金Ⅱ.A基金管理公司和律师事务所达成一致,法律意见书不提及A基金管理公司的子公司情况Ⅲ.A基金管理公司的某高管人员五年前被中国证监会采取市场禁入措施Ⅳ.A基金管理...
经过多年积累,翰森制药已拥有高效的大分子、小分子创新药物发现能力,研发布局覆盖单抗、ADC药物、siRNA、双抗及融合蛋白产品等领域。公司现有超过30个处于临床不同阶段的创新药项目正在开展40余项临床,形成了丰富且具有竞争力的研发管线。 截至目前,公司已有7款创新药获批上市,包括6款首个中国原研1类新药:全球唯一EPO受...