网络发现读框内插入缺失网络释义 1. 发现读框内插入缺失 14.5 发现读框内插入缺失(in-frame indel)14.6 发现其他类型的突变参考文献第15章 小RNA高通量测序数据分析15.1 数据分析流 …book.jd.com|基于13个网页© 2025 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
Several of the tools performed similarly however, VEST-indel had the highest AUCs of 0.93 (full dataset) and 0.87 (DDD subset).#Algorithms designed for predicting the pathogenicity of in-frame indels perform well enough to aid clinical variant classification in a similar manner to missense ...
DNA of polyclonal populations was probed for confirmation of CRISPR-Cas9 indel events near expected cut-site by sequencing PCR products amplified with primers that anneal in introns flanking the targeted exons. Principally observed mutations occurring in these cell ...
This frequency is higher than that of random integration with various indel mutations resulting from the use of donor vectors without homology arms and mediated through NHEJ (53%), suggesting that not only NHEJ but also homology-dependent repair is highly active during early zebrafish development. F...
However, deaf relatives wild type for KCNQ4 did not share a DFNA2 disease haplotype, ruling out the likelihood that the putative mutation was in a non-coding region (or involved an indel not readily detected by Sanger sequencing). The fact that 10 of the 23 relatives of this extended ...
To enable the accurate and rapid quantification of LOF correction efficiency, we first developed a complementary reporter system, which can be used for the rapid and sensitive quantification of recoding efficiency to restore loss-of-function (LOF) mutations (nonsense mutation and frameshift indel mutati...
java -jar InDelFixer.jar -i libCase102.sff -g referenceGenomes.fasta But I encourage to convert the sff to fastq withsff2fastq input.sff -o input.fastqsff2fastqcan be installed with: git clone git://github.com/indraniel/sff2fastq.git; cd sff2fastq; make; ...
Across the genome of this ant mutualist, rates of indel mutation within homopolymeric tracts far exceed the synonymous mutation rate, indicating that long-term conservation of frameshifts within these tracts is inconsistent with neutrality. In addition, the homopolymeric tracts themselves are more ...
必应词典为您提供in-frameindel的释义,网络释义: 读码框位移;发现读框内插入缺失;
M. (2012) Func- tional analysis of in-frame indel ARID1A mutations reveals new regula- tory mechanisms of its tumor suppressor functions. Neoplasia 14, 986 -993B. Guan, M. Gao, C.-H. Wu, T.-L. Wang, and I.-M. Shih, "Functional analysis of in-frame indel ARID1A mutations ...