(1983): In vitro —in vivo correlation, a time scaling problem? Arzneimittelforschung, 33, 598–601.Cardot J.M., Beyssac E., In vitro/in vivo correlations. In: Swarbrick J., Boylan J.C., editors. Encyclopedia of Pharmaceutical Technology 4th Ed Editor, Taylor and Francis Group. 2012...
Evidence showing in vivo correlation between 18F-FDG and 18F-BPA uptakes can provide us with a novel insight that we can expect high BNCT treatment efficacy, even in the tumor sub-volume where glucose consumption is increased. Moreover, fused 18F-BPA PET and 18F-FDG PET/CT images can be ...
An excellent linear correlation (r = 0.997) was obtained between the cumulative dissolved percent in vitro and the cumulative absorbed percent in vivo at each time under certain conditions. This was obtained in vitro with the dissolution rate performed in distilled water (37 °C) with the U.S...
In vitro–in vivo correlations (IVIVCs) of oral solid products have received considerable attention from the industry, regulatory agencies, and academia over the previous years. Defining a quantitative and reliable relationship between in vitro drug release and in vivo absorption is highly desired for...
An in-vivo/in-vitro correlation was established for four formulations of pseudoephedrine sulfate modified release tablets exhibiting different in-vivo and in-vitro release rate and absorption characteristics. In-vitro release rate data were obtained for 12 individual tablets of each formulation using the...
Althoughin vitro–in vivocorrelations (IVIVCs) are commonly pursued for modified-release products, there are limited reports of successful IVIVCs for immediate–release (IR) formulations. This manuscript details the development of a Multiple Level C IVIVC for the amorphous solid dispersion formulation...
In-Vitro In-Vivo Correlation 作者:Afzal Attia; Ahmad Mahmood; Sarfraz Muhammad 页数:208 ISBN:9783659254673 豆瓣评分 目前无人评价 + 加入购书单
In vivo evaluation of two new sustained release formulations elaborated by one-step melt granulation: level A in vitro-in vivo correlation. The objective of this study was to evaluate in vivo two sustained release formulations elaborated by a one-step melt granulation method using theophylline ......
Theory, motivations, methods, in vivo applications, and future directions for improvement and new applications for fluorescence correlation spectroscopy are summarized in this chapter. Introduction Creation of fluorescence correlation spectroscopy (FCS) was originally motivated in the 1960s by a timely ...
PFOA bioaccessibility was negatively correlated with lipid content when assessed using UBM (r = 0.82); however, a poor correlation with food composition was observed for PBET and IVD (r = 0.01-0.50). When in vivo and in vitro data were compared, a strong correlation was observed for UBM (...