Fig. 1: Microglial physical contact with Nodes of Ranvier (NR) in the normal spinal cord. a Schematic of in vivo imaging of mouse spinal cord through an optically cleared intervertebral window with ligamentum flavum (IWLF). b Morphologic components of a myelinated axon. M, myelin sheath; IN...
In vivo imaging in mouse spinal cord reveals that microglia prevent degeneration of injured axonsNEUROGLIACENTRAL nervous systemSPINAL cord injuriesSPINAL cordMICROGLIAPOTASSIUM channelsSODIUM channelsMicroglia, the primary immune cells in the central nervous system, play a critical role in regulating ...
The spinal cord accounts for the main communication pathway between the brain and the peripheral nervous system. Spinal cord injury is a devastating and largely irreversible neurological trauma, and can result in lifelong disability and paralysis with no
Screenshot of mouse brain atlas Neuroanatomy of the mouse brain Ischemia/hypoxia stroke model View all Publications 01/ 09 previous slide next slide TOP PAPER In vivo imaging in experimental spinal cord injury – Techniques and trends Brain and Spine ...
In vivo two-photon laser scanning microscopy (2PLSM) of neurons and glia in the mouse neocortex can be achieved using two distinct surgical methods: the th... M Isshiki,S Okabe - 《Microscopy (Oxford》 被引量: 14发表: 2013年 Two-photon calcium imaging in the intact brain. The is a ...
In vivo imaging of single axons in the mouse spinal cord. Nat. Protoc. 2, 263–268 (2007). Article CAS Google Scholar Farrar, M.J. et al. Chronic in vivo imaging in the mouse spinal cord using an implanted chamber. Nat. Methods 9, 297–302 (2012). Article CAS Google Scholar F...
Ex vivo autophagy imaging of spinal cord sections (20 μm) also showed a progressive increase of the fluorescence signal from 17 to 19 weeks in DTg mice in the anterior horn at the L4-5 level, and the fluorescence signals were clearly observed in the gray matter of the spinal cord with ...
We conclude that the MDR1-luc mouse provides a unique in vivo system to visualize MDR1 CNS expression and regulation. The American Society for Pharmacology and Experimental Therapeutics. 展开 DOI: 10.1124/dmd.115.065078 被引量: 1 年份: 2015 ...
In vivo hepatic balances for glutamine, glutamate, alanine, and urea were performed on anesthetized animals by simultaneous measurement of flow through the ... T Welbourne,S Joshi,R Mcvie - 《American Journal of Physiology》 被引量: 121发表: 1989年 In vivo monitoring of glutathione and cystein...
In vivo imaging in mouse spinal cord reveals that microglia prevent degeneration of injured axons Article Open access 13 October 2024 Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury Article Open access 02 March ...