M. Hassan, In vivo and cytotoxic assays of a poly(vinyl alcohol)/clay nanocomposite hydrogel wound dressing. J. Biomat. Sci.-Polym. E 22, 1023 (2011).Sirousazar, M., Kokabi, M. and Hassan, Z.M. ``In vivo and cytotoxic assays of a polyvinyl alcohol/clay nanocomposite hydrogel wound...
1.12.1.1In vivo studies The study of the hazardous effects of chemical substances on a living organism, such as a laboratory animal, is known as in vivo toxicology. Different in vivo toxicity assays are performed, such as dose-range finding assay, single and repeat-dose toxicity assay, acute...
In vivo OVA-specific Cytotoxic CD8+ T Cell Killing Assay Cytotoxic CD8+ T cells are responsible for the lysis of cells expressing peptides associated with MHC class I molecules and derived from infection with a p... N Chaoul,C Fayolle,C Leclerc - BIO-PROTOCOL 被引量: 0发表: 2016年 In ...
To test for effector functions of the induced T cells, we performed an in vivo cytotoxicity assay. BALB/c mice were DNA vaccinated once by i.d. or i.m. immunization and injected 2 weeks later with cell trace violet (CTV) labeled splenocytes pulsed with the IYSTVASSL peptide (or a ...
For the inhibition of BChE in the rat brain slices, the in-vitro cytotoxicity assay, the in-vivo blood plasma to brain distribution assay, and the in-vivo activity assays, compound 2 was used in the form of its hydrochloride salt (see Supplementary Scheme S2, Supplementary Methods). All ...
Their toxic/antitoxic, genotoxic/antigenotoxic, and chronic toxicity (lifespan assay) effects were determined in vivo using the Drosophila model. Their cytotoxic activities were determined using the HL-60 in vitro cancer model. In addition, clastogenic DNA toxicity was measured using internucleosomal ...
Finally, the in vivo effects of nanoscale and conventional photosensitizers on liver cancer were assessed in nude mice. Nanoscale Photosan-II significantly inhibited hepatoma cell viability in a concentration-dependent manner and this effect was more pronounced with high laser doses. Moreover, ...
Cytotoxicity assay Cell viability was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, which was based on the ability of mitochondrial succinate dehydrogenase in living cells to reduce yellow tetrazolium salt to violet formazan compounds. In a typical...
In cytotoxicity studies, some additive effects (32‒43%) were observed when CT26 cells were treated with both boron- and gadolinium-encapsulated PEGylated liposomes (B- and Gd-liposomes) compared to the single treatments. The tumor-suppressive effect was greater when BNCT was followed by GdNCT ...
In vivo NCG-HuPBL mouse model for the in vivo CD3+CD4+ depletion assay NCG mice were purchased from GemPharmaTech. NCG mice were maintained in accordance with the Guide for the Care and Use of Laboratory Animals of the Medical School of Nanjing University. All experiments were performed accordi...