Our findings indicate that the wake slow waves we identified are associated with a reduction in excitability and a beneficial impact on IEDs; and this opens promising therapeutic perspectives. In this context, the specificity of low-frequency (1–3 Hz) stimulation to elicit synaptic depression ...
In this Foreword I offer a brief and highly selective historical analysis of topics in platelet history, with the hope of providing both a sense of the sweep of intellectual development in the field and a context for understanding our current concepts and likely future directions. Those interested...
A limitation of this study is that it was an observational study dealing with technical issues and not a randomized study comparing different subgroups of patients. In this context, the ethical question remains as to what extent an awake patient can endure the psychologic stress of such an ...
In the context of a simplex (single-target) reaction, all of these can be optimized at will, but if the goal is a multiplex reaction, things get a lot more complicated. Selecting all primer sets to have similar melting temperatures is probably the most crucial step, and to do so while ...
After COVID-19, dysfunctional EC can synthesize and release several factors that are crucial regulators of coagulation and thrombosis [61]. The role of such regulators and how their delicate balance is disrupted in the context of COVID-19 is briefly reviewed over the next sections. ...
devoid of hematopoietic toxicity or endothelial injury. In an in vivo model, it has been observed that CAR.CD123-NK cells and CART123 cells exhibit distinct toxicity profiles in this particular context [119]. The outcomes of this model revealed that CAR.CD123-NK cells do not exhibit targeting...
This is a randomized, controlled, double-blind, single-dose, single-center parallel-group clinical trial to assess the effects of a single dose of amisulpride (100 mg) on blood-oxygenation-level-dependent (BOLD) responses during reward- and motivation-related processing in healthy subjects (n ...
The paper is structured as follows: In the next section, the physico-chemical soot model and the mathematical background of MOMIC in the context of this model are reviewed. Then, in Section 3, the investigated test cases for model analysis and validation are discussed. To maximize the generali...
Therefore, the down-regulation of this receptor in these data is potentially surprising, however it suggests other mechanisms are capable of reducing NF-ĸβ activation in this complex system, so lowering EPRC may be beneficial in this context. In addition, thrombin activation or EPCR produces ...
there are indications of general regularities in the way we express our thoughts and emotions to other people. (In this context even a volume of speech over telephone might be considered a derivative of the intention to be heard by the listener.) Unfortunately, as most of the studies focused ...