FAK and WNT Signaling: The Meeting of Two Pathways in Cancer and Development Recent studies connect the FAK and Wnt/尾-catenin signaling pathways, both which promote cancer when aberrantly activated in mammalian cells. Over-stimulat... Y Fonar,D Frank - Anti-Cancer Agents in Medicinal Chemistry...
signaling pathwaysNo Abstract available for this chapter.doi:10.1007/978-1-59745-470-4_8Daniel KalderonHumana PressD. Kalderon, "Signaling Pathways in Cancer," in Principles of Molecular Oncology (M. H. Bronchud and E. al, eds.), ch. 8, pp. 153-188, Totowa, NJ: Humana Press, 2008....
Since Warburg discovered aerobic glycolysis as a metabolic marker of cancer cells, extensive studies have enhanced our understanding of the metabolic changes in cancer cells.1,2,3,4,5Metabolic reprogramming is a common feature of many tumors, enabling cancer cells to meet their specific growth requi...
Several major signal cascades affect not only the biological behaviors of CAFs themselves but also the crosstalk between CAFs and cancer cells. Therefore, in this section, we will discuss how signaling pathways regulate the CAFs, the crosstalk of CAFs with cancer cells, and the targeted therapies....
In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, ...
Abstract 2081: Evaluation of Src as a therapeutic target in biliary tract cancer using bosutinib, a c-Src/Abl kinase inhibitor. Background: Src is a nonreceptor tyrosine kinase involved in the crosstalk and mediation of many signaling pathways that promote cell proliferation, invasi... AR Nam,...
Signaling Pathways in Squamous Cancer 作者:Waes, Carter Van 编 页数:482 定价:$ 236.17 ISBN:9781441972026 豆瓣评分 目前无人评价 评价: 写笔记 写书评 加入购书单 分享到
signaling pathways in GC are not well understood.Here,we review the regulatory roles of signaling pathways in GC potential biomarkers,and therapeutic targets with an emphasis on recent discoveries.Current therapies,including signaling-based and immunotherapies exploited in the past decade,and the ...
KEGG 通路富集分析结果显示熊果酸作用于宫颈癌的靶点主要涉及 pathways in cancer、TNF signaling pathway、PI3K-Akt signaling pathway、apoptosis 等信号通路。宫颈癌进展分为四个阶段:一期宫颈癌癌细胞仅发生在子宫颈上皮区域,属于原位癌;二期...