Drug delivery to the gastrointestinal (GI) tract is highly challenging due to the harsh environments any drug- delivery vehicle must experience before it releases it’s drug payload. Effective targeted drug delivery systems often rely on external stimuli
LNPs in the GI tract, with an ultimate goal of oral LNP delivery. However, the environment of the GI tract has proven to be a stability challenge for countless drugs and delivery vehicles. Herein, we evaluate LNP fate and function in the GI tract to improve our understanding of LNP potenti...
Although elaborately explained the roles of the brain derived neurotransmitter in terms of their neuroactivities, the function of KP metabolites in the gastrointestinal (GI) tract still remains poorly understood [56]. To unravel the underlying relationships among KP metabolism, microbial composition and ...
(2) Working alone. Especially, when endoscopists detect the narrow-body cavities such as pancreatic duct and biliary tract. Moreover, these techniques can also be categorized based on the way how light interacts with tissues while detecting, such as reflection, absorption, elastic scattering, inel...
(EEC), central nervous system (CNS), enteric nervous system (ENS), vagus nerve, and gut microbiota. EECs are specialized trans-epithelial cells found throughout the gut [169]. The ENS, the nervous system of the gastrointestinal tract, consists of various types of neurons, including intrinsic ...
1.1. The importance to characterize the human gut microbiome The human gut microbiome (GM) is a complex ecosystem of microorganisms including bacteria, viruses, archaea and eukaryotes and their genetic entities colonizing the gastrointestinal tract. It is involved in numerous host functions such as nut...
Book2009,Surgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas (Second Edition) ARIEF A.SURIAWINATA, ...SWAN N.THUNG Explore book IN SITU HYBRIDIZATION Forin situ hybridization, radioactively labeled probes for specific RNA or DNA sequences are applied and hybridized to a tiss...
We demonstrate that a specific stem cell population, distant from the original injury, originates long-lasting wound memory progenitors residing in their own niche. Notably, these distal memory cells have not taken part in the first healing but become intrinsically pre-activated through priming. ...
Because interactions between the microbiome and the host are more direct in the GI tract than in other organs, we can postulate that appendectomy critically affects the pathogenesis of malignancy by interrupting the microbial ecosystem in the GI tract. However, only a few studies have examined the...