However, after acute permeability barrier disruption, both aged mice and humans (>75 years of age) have a delay in permeability barrier recovery associated with a decrease in lamellar body secretion and extracellular lipids in the stratum corneum (5). A decrease in both cholesterol synthesis and ...
oil is the term generally used to refer to lipids that are liquid at room temperature and of vegetable origin, while fat refers to lipids that are generally solid at room temperature and of animal origin. For example, flaxseed, soybean, and sunflower oils have a melting point...
In VSMC calcification, although autophagy is more beneficial to cell survival and ameliorating VC to some certain extent, most PCD is accompanied by an increase in inflammatory mediators and oxidative stress, which enhances the pro-calcific microenvironments and causes more damage to the tissue. ...
Both a supervised method (PLS-DA) and an unsupervised method (PCA) were carried out to discriminate the differences in lipid profiles between the two groups. To screen for differential metabolites, VIP > 1 and p<0.05 were used, and p<0.05 was typically fixed. Finally, the lipids were...
Possible explanations for this result is that serum levels were below the detection limit of the method, or most of the absorbed FB1 bound to serum components such as lipids or serum proteins, hence making the free toxin undetectable. In our study, the high sensitive LC-MS/MS method used ...
J. et al. Lipids partition caveolin-1 from ER membranes into lipid droplets: updating the model of lipid droplet biogenesis. FASEB J. 18, 866–868 (2004). Article CAS PubMed Google Scholar Wältermann, M. et al. Mechanism of lipid-body formation in prokaryotes: how bacteria fatten up...
High Lp(a) level was previously considered a risk factor for thrombosis and might have the additive effects on atherosclerosis in certain pathological conditions[5]. High Lp(a) level is known to increase the risk of atherosclerotic events such as cerebrovascular and cardiovascular disease (CVD)[6...
Lipids are essential building blocks synthesized by complex molecular pathways and deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found in almost all organisms, from bacteria to mammals. They are composed of a hydro
The widely reported associations between body mass index (BMI) and various chronic diseases, such as hypertension and asthma, have garnered significant attention. Nonetheless, there remains a dearth of research dedicated to understanding the health impac
Most of the developed nations exert certain levels of regulations and have developed reliable strategies for the monitoring of safety and standardization of these products while providing quality assurance for any of such natural substance [5,6]. However, many traditional and complementary medicine ...