必应词典为您提供in-situ-click-chemistry的释义,网络释义: 原位点击化学;原位点击化学作用;
V. Lee et al., "In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II," Angewandte Chemie International Edition, vol. 44, no. 1, pp. 116-120, 2004.MOCHARLA V P,COLASSON B,LEE L V,et al.In situ click chemistry:enzyme-generated inhibitors of carbonic anhydrase ...
网络原位点击化学 网络释义 1. 原位点击化学 原位点击化学(click chemistry in situ) 已被用来发现多种酶的高亲和力的抑制剂,包括重要的神经递质酶( neurotransmitter enzym… hi.baidu.com|基于5个网页
药物开发领域中的“点击化学”“ClickChemistry”indrugdiscovery2005级博士生:葛广波20060517指导老师:**研究员Outline“点击化学”的产生背景“点击化学”的定义及特征“点击化学”在药物开发中的应用“原位点击化学”(InSituClickChemistry)“点击化学”展望OceanofCompoundsHitLeadINDCandidateDrugDrugDiscoveryandDevelopment:...
(ii) the azide component should have a proper size and orientation that will not interfere with the entry of the alkyne component into the COX-2 active site, allowing the in situ click chemistry formation of a potent and selective inhibitor large enough to block the hydrophobic channel of the...
药物开发领域中的“点击化学” “ Click Chemistry” in drug discovery 2005级博士生:葛广波Outline “点击化学”的产生背景 “点击化学”的定义及特征 “点击化学”在药物开发中的应用 “原位点击化学”(In Situ Click Chemistry) “点击化学”展望 Drug Discovery and Development: --- a laborious process !!!
“ClickChemistry”indrugdiscovery指导老师:杨凌研究员 2005级博士生:葛广波20060517 Outline •“点击化学”的产生背景•“点击化学”的定义及特征•“点击化学”在药物开发中的应用•“原位点击化学”(InSituClick Chemistry)•“点击化学”展望 产生背景 DrugDiscoveryandDevelopment:---alaboriousprocess!!!Oc...
In situ click chemistry method for screening high affinity molecular imaging probes 发明人: KOLB HARTMUTH C.;MOCHARLA VANI P.;WALSH JOSEPH C. 申请人: 申请日期: 2006-04-27 申请公布日期: 2006-11-30 代理机构: 代理人: 地址: 摘要: The invention provides a method for identifying a candi...
“ClickChemistry”indrugdiscovery指导老师:杨凌研究员 2005级博士生:葛广波20060517 Outline •“点击化学”的产生背景•“点击化学”的定义及特征•“点击化学”在药物开发中的应用•“原位点击化学”(InSituClick Chemistry)•“点击化学”展望 产生背景 DrugDiscoveryandDevelopment:---alaboriousprocess!!!Oc...
In situ click chemistry is a target-guided synthesis technique for discovering potent protein ligands by assembling azides and alkynes into triazoles inside the affinity site of a target protein. We report the rapid discovery of a new and potent inhibito