Conclusion: The apoptosis was a spontaneous phenomenon in breast cancer tissue, and the expression was different from each other. Further analysis was needed to clarify the relationship between apoptosis and prognosis, especially the response to adjuvant therapy....
Claudin-4 Expression Is Associated With Disease-Free Survival in Breast Carcinoma-in-Situ: Mean Follow-up of 8.2 Years Claudins are tight junctions associated with breast cancer prognosis. The claudin-low intrinsic subtype of invasive carcinoma is associated with high-grade... GM Duarte,NR Almeida...
Histological grading, when adequately carried out, provides a simple, inexpensive, and highly accurate method for assessing tumor biological characteristics and patient prognosis. This is of particular importance for breast cancer patients in parts of the world where access to new molecular technology is...
6 This study has been criticized for its absence of central pathology review to exclude occult invasive breast cancer, its retrospective nature with inherent selection bias, and its survival statistical methods.7–9 Despite these limitations, the study clearly demonstrates the excellent prognosis of ...
Prognosis in women with a carcinoma in situ of the breast: a population-based study in Sweden We studied the risk of invasive breast cancer and breast cancer death after a breast carcinoma in situ during a period when mammography screening became a ... F Wrnberg,J Bergh,L Holmberg - Canc...
LesionsBreast CancerPrognosiscancer riskPremalignant breast lesions pose variable risks for transformation, raising the question who should receive treatment to counteract the potential progression to breast cancer. Because the secreted metastasis mediator Osteopontin (OPN) is a marker for breast cancer ...
Analysis of telomerase activity levels in breast cancer Consequently, an in situ analysis would seem to be important to identify the nature of telomerase-positive cells. Immunocytochemical detection of the hTERT ... NW Kim,D Levitt,G Huang,... 被引量: 1发表: 1996年 DETECTIONOFTELOMERASEACTIVITY...
with distant metastasis and poor prognosis in breast cancer [16,17,18]. Breast tumour hypoxia and HIF-1α-regulated gene expression contribute to aggressive tumour behaviour and seeding of cancer cells with a metastatic capacity [47,48].
Breast cancer is a malignant tumor mostly disclosed in women. It has heterogeneous biological behavior - so that the knowledge of tumor markers is very important to determine its prognosis and therapy. Up to now, the determination of prognosis and treatment of choice is still based on clinical ...
breast cancer prognosis, which participate in hormone receptor modulation, response to growth factors and targeted therapies.64,65,66The MAPK pathway is activated in approximately 50% of breast cancers.67RAS mutation, which frequently observed in tumors such as pancreatic cancer and colorectal cancer,...