In silico是指“在硅之中”,也就是“进行于电脑中,或是经由电脑模拟”之意,此用语是衍生自另外两个在生物学上常用的词组:in vivo(生物活体内)及in vitro(生物活体外) 。但与这两个词组不同的是,in silico在拉丁文中并不存在。
1.拉丁文In silico直译是“在硅上”,ln silico analysis其实就是指通过计算机或者计算机模拟来分析。因为计算机的使用的超大规模集成电路主要材料都是硅,所以有这个诙谐的说法。2.in silico有电子的意思,表示计算机,in silico prediction就是计算机预测,还可以表示生物信息学,in silico prediction在生物...
求翻译:In silico prediction of the functional effect of the p.R67C amino acid substitution obtained with PANTHER indicated that it is highly probable that this amino acid change causes a deleterious effect on the normal functionality of the MC1R protein (subPSEC =−6.68827; Pdeleterious = 0....
In Silico Prediction of Inhibition of Promiscuous Breast Cancer Resistance Protein (BCRP/ABCG2) Breast cancer resistant protein has an essential role in active transport of endogenous substances and xenobiotics across extracellular and intracellular m... YL Ding,S Yu-Hsuan,T Fu-Yuan,... - 《Plos...
Data for: In silico prediction of human genes as potential targets for rice miRNAs With food, a huge variety of biological material gets into the human digestive tract, which the body uses for life support. The variety of food material entering the gastrointestinal tract, especially at the molec...
Deep Learning Based Regression and Multi-class Models for Acute Oral Toxicity Prediction with Automatic Chemical Feature Extraction Median lethal death, LD50, is a general indicator of compound acute oral toxicity (AOT). Various in silico methods were developed for AOT prediction to red... Y Xu,...
High-throughput computational methods capable of predicting, evaluating and identifying promising synthetic candidates with desired properties are highly appealing to today’s scientists. Despite some successes, in silico design of crystalline materials
Analysis of drug–target interactions (DTIs) is of great importance in developing new drug candidates for known protein targets or discovering new targets for old drugs. However, the experimental approaches for identifying DTIs are expensive, laborious a
In silico prediction of novel therapeutic targets using gene–disease association data 来自 EBSCO 喜欢 0 阅读量: 112 作者:E Ferrero,I Dunham,P Sanseau 摘要: Target identification and validation is a pressing challenge in the pharmaceutical industry, with many of the programmes that fail for ...