At a particular locus, this was achieved by including families where only the mother, or both the mother and the father are heterozygous when summing transmitted alleles. This analysis will thus describe a composite of female and male transmission patterns, although females contribute more than ...
Affected individuals have a normal male 46, XY karyotype and they are phenotypic females, but they have streak gonads and are consequently sexually immature and sterile. Pedigrees are consistent with either X-linked or autosomal dominant inheritance of a gene which inhibits maleness in XY ...
Data for PCR-positive cats and dogs are summarized in Table 2. Among the T. foetus-positive cats (n = 13), there were more females (69.2%) than males (30.8%), while both P. hominis-positive cats were females. Based on this, there was no significant correlation between PCR positiv...
To make matters worse, excision of such nuclei in rats causes only transient disturbance to sexual behavior and in monogamous prairie voles, the sexually dimorphic nuclei, whose differences between adolescent males and females are evident, become difficult to differentiate in parentally engaged bonded ...
Figure 2. Pedigrees of the Fabry families with non-F113L GLA gene variants. The screening also found two males with residual enzymatic activity of α-galactosidase A, carrying respectively the p.A143T (0.15 nmol/h/spot) and p.R118C (0.23 nmol/h/spot) variants; two females with the p....
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Introduction Breast cancer is by far the most frequently diagnosed malignant tumour in females: one Swedish woman in ten will be affected during her lifetime [1]. Most cases occur late in life and are sporadic. A Scandinavian twin study has revealed that hereditary factors are important in 27...
[4,5,6,7]. The initial discovery was made nearly 30 years ago by linkage analysis of pedigrees [4] and over the ensuing years it has become the most highly replicated genetic risk factor for LOAD [4,5,6,7]. Subsequent large multi-center genome-wide association studies (GWAS) have ...
1 Pedigrees showing the crossing scheme with the sex ratios and sample sizes. Sex ratios are represented by the pie diagrams, with the black portion representing the proportion of males. The entire crossing design was repli- cated five times, and the sex ratios are pooled across replicates. ...
It may be significant that only Sv females were present in pedigrees 1891 and 2669 while all XYGn fish were males. This suggests that whatever factors are responsible for occurrence of XY females interact with the V chromosome marked by Sv and not with the one marked by Gn. Since Ga is ...