The fundamental basis of the genetic disorders is the imperfectness of the machinery that replicates the genome during meiosis. The DNA polymerases and the editing enzymes afford the genome a near perfect but not an absolute precision in DNA replication. The estimated error rate of 10~8 error ...
These results thus showed that DNA recombination might be affected in A1. Table 2 DEGs involved in homologous chromosome behavior during meiosis. Full size table In addition, specific sequence distribution, chromosome morphology, and the chromosome condensation patterns that give a chromosome a ...
In order to evaluate the in vivo function of the SUN1–SPDYA interaction during meiosis, we generated knock-in mice with a SPDYA-binding-deficient mutation W151R in the Sun1 gene using the CRISPR-Cas9 method (Supplementary Fig. 4a). The heterozygous mice appeared healthy and fertile and were...
Anther development is crucial for male fertility and sexual reproduction in plants [1]. Cells in an anther undergo meiosis to produce microspores, which further develop into mature pollen grains [2]. According to morphological features, anther development can be divided into 14 stages: during stage...
Centromeres play a critical role in ensuring the accurate segregation of chromosomes during both mitosis and meiosis [1], being specialized chromosomal regions associated with chromatid cohesion and correct separation during cell division. Centromeres serve as the assembly and attachment points for the ...
Using RNA-seq to profile gene expression of spikelet development in response to temperature and nitrogen during meiosis in rice (Oryza sativa L.). PLoS One. 2015;10(12):e0145532. Article PubMed PubMed Central Google Scholar He Q, Lin Y, Tan H, Zhou Y, Wen Y, Gan J, Li R, ...
Recombinants are derived from two homologous chromosomes in one genome during meiosis (genic recombinants) or PCR (artifacts), leading to incorrect phylogenetic inferences [78–80]. As predicted by statistical principles, we found that putative recombinants formed separated clades. Recombinants ...
(FOXG_16456). FOXG_14161 encodes a protein homologous to the eukaryotic conserved kinetochore protein Mis12 that is involved correct segregation of daughter chromatids during mitosis and meiosis [29]. FOXG_14165 encodes a protein with a BAH (bromo-adjacent homology) domain which may interact ...
The mixture of flower buds with different sizes were collected in the afternoon during flowering period, immediately placed in liquid nitrogen, then stored at −80 °C for qRT-PCR. All qRT-PCR reactions were performed with three biological replicates. SXCMS5A and SXCMS5B were planted in the ...
The 24-nt reproductive phasiRNAs are triggered by miR2275, and are highly enriched during meiosis in many angiosperms. Here, we report the widespread presence of the 21-nt reproductive phasiRNA pathway in eudicots including canonical and non-canonical microRNA (miRNA) triggers of this pathway. ...