Medical coding speed and accuracy issues Transformation of diagnoses, procedures, services, treatment plans, and other concepts into medical codes involves a lot of manual work, performed by specially trained professionals. Today coders rely on computer-assisted coding systems. However, the speed and ...
Pneumococcal disease has a high burden in adults in the United Kingdom (UK); however, the total burden is underestimated, principally because most cases of community-acquired pneumonia (CAP) are non-invasive. Research into pneumonia receives poor funding relative to its disease burden (global morta...
This study compared different approaches for monitoring progress towards Sustainable Development Goal Target 4.2, which focuses on the proportion of childr
This cross-sectional study analyzes the prevalence of stigmatizing language in the electronic health records at a large academic medical center.
Advanced prostate cancer (PCa) often develops bone metastasis, for which therapies are very limited and the underlying mechanisms are poorly understood. We report that bone-borne TGF-β induces the acetylation of transcription factor KLF5 in PCa bone metastases, and acetylated KLF5 (Ac-KLF5) causes...
A tendency to look at the left side of faces from the observer’s point of view has been found in older children and adults, but it is not known when this face-specific left gaze bias develops and what factors may influence individual differences in gaze lateralization. Therefore, the aims...
Exome sequencing is a special type of targeted method to sequence protein-coding regions of the genome, called the exome [7]. While making up only about 1–2% of the human genome, the exome harbors approximately 85% ...
doi:10.1001/jamanetworkopen.2021.41089 Key Points Question What are the incidence and outcomes associated with posttransplant Clostridioides difficile infection (CDI) in people who have undergone solid organ transplant? Findings In this cohort study including 10 724 patients, posttransplant CDI was ...
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Many bacteria and archaea possess a two-dimensional protein array, or S-layer, that covers the cell surface and plays crucial roles in cell physiology. Here, we report the crystal structure of SlpA, the main S-layer protein of the bacterial pathogen Clos