2004. Ureagenesis: evidence for a lack of hepatic regulation of acid–base equilibrium in humans. Am. J. Physiol. Renal Physiol. 286 : F94-F99 CrossRef , Medline .Hosch M, Muser J, Hulter HN, Krapf R: Ureagenesis: evidence for a lack of hepatic regulation of acid-base equilibrium ...
Retention solutes found at higher levels in uremic subjects have been identified as uremic toxins based on their association with uremic symptoms in animals and humans with renal failure, the resolution of these symptoms when levels of these compounds are lowered, and the toxic effects when these ...
In normal adult humans, about 90% of ingested me- thionine is converted to cyst(e)ine [21], a nonessential amino acid, via the transsulfuration pathway (Fig. 1). 538 Development of mammalian sulfur metabolism 539 A key intermediate of this pathway is cystathionine, which is normally ...
Moreover, in alternative work, it was displayed that this impact of rapidly cumulative phagocytosis by growing extracellular compression may also be discovered in primary monocytes in humans and monocyte-derived phagocytes.66It is known that p38 mitogen-activated protein kinase (MAPK) is a further c...
elutes from different HPLC columns is analyzed by HPLC; 3) the carboxyterminal and amino terminal analysis should yield only one amino acid; 4) the material should yield a single band in polyacrylamide gel electrophoresis with SDS and at an acidic pH in presence of high concentrations of urea...
Additionally, among the cold tolerance-related PSGs detected for Chantecler by two methods [24], six genes were revealed in USH:PLCZ1,TYR(known as a key gene for skin lightening in humans associated with cold adaptation in humans as reviewed in [24]),HTR5A,EML5,LRP2, andKIF1B. ...
Efforts in developmental drug metabolism in vitro with animal models are aimed at obtaining data which have some utility in predicting the clinical efficacy and/or toxicity of drugs. In vitro studies involving purified isoenzymes, subcellular fragments (
Many variations in known or suspected DNA binding sites for TFs have been recognized, their impact on gene expression determined in cell lines and clinical expression recognized in humans [40]. A number of examples is shown in Table 1. This shows that most mutations have been identified in a...
Chemicals specific for protein analysis: formic acid (VWR, 84865-180P), ULC/MS-grade methanol (VWR, 83638320), ULC/MS-grade water (Honeywell, 14263-2L), ULC/MS-grade ACN (Honeywell, 34967-2.5L), urea (Merck, 1084871000), triethylammonium bicarbonate (TEAB) (Sigma-Aldrich, 18597-100ML)...
Inheritance and clearance of maternal mRNAs are two of the most critical events required for animal early embryonic development. However, the mechanisms regulating this process are still largely unknown. Here, we show that together with maternal mRNAs, C