pioneering “induced pluripotent stem cell” (iPSC) technology is an ethically acceptable and robust method to convert differentiated cells to pluripotent cells, which can then be directed to produce specific cell types using the requisite factors, for tissue repair and therapy. The mechanisms underlyin...
COVID-19 is a major worldwide health problem because of acute respiratory distress syndrome, and mortality. Several lines of evidence have suggested a relationship between the vitamin D endocrine system and severity of COVID-19. We present a survival study on a retrospective cohort of 15,968 pa...
As the concentration dependent effects of vit.D on the immune system and the means to achieve such concentrations safely in the shortest possible time in a given individual is known19,30,32, we have carried out this study to determine the impact of Pulse D therapy on the inflammatory markers...
The objective of this paper is first to investigate this information asymmetry by studying the identity of a panel of equity funds according to (i) the ESG signals sent by the managers (e.g., the choice of fund name or the choice of certification via a label—the de jure ESG) and (ii...
(A) targeting e system cancers by micrH(oAGR)NFt/Aac-rsMg.e(EtAiTn)gitnaHrgHGeCFti/Cncg-bMHyEGmTFi/RicnN-MHAECsT;C(iBnb)yHmmCiRiCRNNbAAyss-mH; (iGRBFN)/mcA-MsiR; EN(BTA)asmx-HiisRGiNFn/Agcsa--MHstrEGicTF/caca-xMniscEeirTn; ga(Cxais)strminciRcgNaanAsctsrei-rc; cancer; (C...
19,24 Similar to what is obtained for other therapeutic modalities, activation of survival pathways has emerged as a major mechanism of resistance to PDT. It is now known that post-PDT, tumor cells activate signal transduction pathways that mediate PS extrusion, pro-surv...
(e.g. Mason, 2002; Davidson et al., 2011). Groundwater is often assumed to be of higher water quality with less contamination that surface waters, and thus is presumed to be high quality water resources for human consumption. However, shallow or unconfined aquifers can be susceptible to ...
The lack of checks and balances results in a leak of public funds for development, and the health sector is not spared. Most countries in the region already have low budgetary allocation for the health sector and depend highly on donor agencies to supplement their budgets. Most countries within...
CB1 is the predominant G-protein coupled receptor (GPCR) in the mammalian brain, while CB2 is highly expressed in immune cells [47]. Their activities are primarily associated with neuroprotective and anti-inflammatory actions, emphasizing the critical role of maintaining homeostatic EC balance for ove...
[6]. An adult 8–10 week old BL6 adult female mouse, with a weight of 16 g and a liver weight of 1.25 g, bears approximately 1.5 × 108or 150 million hepatocytes [6]. A key point is that replacing about 10% of liver function, which is still a large mass of cells, can support...