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Monitoring the progression of Tau pathology makes it possible to study the clinical diversity of Alzheimer’s disease. In this 2-year longitudinal PET study, we aimed to determine the progression of [18F]-flortaucipir binding and of cortical atrophy, and their relationships with cognitive decline...
Anatomical T1-weighted images were acquired using the following acquisition parameters: 1 mm109 resolution, repetition time (TR): 7.7 ms, echo time (TE): 3.6 ms, flip angle: 8°. MRI preprocessing Data collected for individuals of whom we tested the left foot was flipped on the ...
An anatomical substrate for integration among functional networks in human cortex. J. Neurosci. 33, 14489–14500 (2013). Article PubMed PubMed Central CAS Google Scholar Dum, R. P., Levinthal, D. J. & Strick, P. L. Motor, cognitive, and affective areas of the cerebral cortex influence...
All patients suspected of having systemic disease were referred to a rheumatologist. The final diagnosis was made according to the International Uveitis Study Group classification [7]. Uveitis was classified using its anatomical location as anterior, intermediate, and poste- rior uveitis and panuveitis...
(non-targets). No prefrontal region demonstrated greater activity for new items in the exclusion task. Thus, there was no evidence that retrieval cues were processed differently according to the specificity of the sought-for information. In several regions, most notably bilateral anterior prefrontal ...
(Fig.3). The cell counting revealed the difference in the morphology of the disc floret was caused by an increase in cell number and length. Anatomical observation of the two types of florets revealed that the adaxial cells of NAT disc floret were degraded, and only the adaxial cells were...
have been considered the primary component of a model’s credibility. Thus, for the most part, equating the credibility of the practice to evaluation of validity of the model or model outputs. The present study takes a comprehensive approach by treating credibility as a term inclusive of ...
individual differences in MTL subregion morphology59. Notably, the chosen Magdeburg Young Adult 7T Atlas34leverages information on anatomical variability, resulting in a more accurate delineation of the boundary between the CA1 and subiculum, CA3 and dentate gyrus, as well as the parahippocampal ...
These results constitute a critical advance in our understanding of PFC function. A quintessential node in the perception-action cycle, PFC has long been considered crucial for temporal organization of goal-directed behavior62,63. This is aided by its brain-wide anatomical connectivity, which includes...