Answer to: In genetic code, what does it mean "to code for"? (For example codons code for an amino acid, DNA and RNA code for proteins,)? By...
2. DNA damage in organelles 3. Mitochondrial DNA repair mechanisms: the BER pathway 4. Mitochondrial DNA repair mechanisms: further pathways 5. Specific aspects and further factors of organelle DNA repair mechanisms 6. Sub-organellar localization of DNA repair 7. Mitochondrial DNA damage, genetic pr...
Sequencing of PCR products confirmed that the donor DNA is integrated at the correct position and that mRNA splicing of the last two exons was unaffected by the integration (Supplementary Fig. 17d, e). As the editing happens in the intron and 3′ UTR, the main advantage of TKIT approach ...
Repetitive DNA sequences playing critical roles in driving evolution, inducing variation, and regulating gene expression. In this review, we summarized the definition, arrangement, and structural characteristics of repeats. Besides, we introduced diverse biological functions of repeats and reviewed existing...
If the base sequence along a segment of DNA were TCGTA, what would be the antisense oligonucleotide synthesis from this sequence? List the anticodons to which the following codons would form base pairs: 1. What is the complementary strand of DNA re...
All living species contain genetic information that was once shared by their common ancestor. DNA is being inherited through generations by vertical transmission (VT) from parents to offspring and from ancestor to descendant species. This process was con
It may be that these genes in general require especially tight transcriptional regulation, with a consequence being they are less accessible for DNA repair. Chromatin structure is likely, however, to be only one of a number of factors that are associated with the variance in divergence rates ...
Recent discoveries on bacterial transcriptomes gave evidence that small RNAs (sRNAs) have important regulatory roles in prokaryotic cells. Modern high-throughput sequencing approaches (RNA-Seq) enable the most detailed view on transcriptomes offering an
and stable, a suitable length of poly(A) must be added to it, either directly from the encoding DNA template or by using poly(A) polymerase [81]. The codons utilized also affect protein translation [82]. It is typical practice to replace unusual codons with common synonymous codons that...
What other features might distinguish m6A-enriched and m6A-depleted transcripts? Motif analysis revealed GAGA motifs within the promoters of m6A-enriched transcripts (Extended Data Fig. 9e). GAGA factor (GAF) is a DNA-binding transcription factor that binds GAGA motifs and is associated with promot...