In contrast to normal mice, FOXA1- and FOXA2-deficient mice exhibit hyperglycemia and die shortly after birth [20]. Further studies have shown that FOXA1 and FOXA2 are synergistically involved in regulating Pdx1
DeDivisionCarolisDivisionSerenaDivisionADivisionRubortoneDivisionCarmenDivisionCoccaDivisionGiovanniDivisionSpringerItalian Journal of PediatricsDe Carolis MP, Rubortone SA, Cocca C, et al.. Hypoglycemia and hyperglycemia in extremely low-birth-weight infants. Ital J Pediatr. 2015;41(Suppl 1):A7....
Diabetic Hyperglycemia Non-Diabetic Hypoglycemia in Childhood Symptoms and treatments Diabetes mellitus Hypoglycemia Type 1 Diabetes Mellitus Medicine.com guides (external) Diabetes Guide Further information Always consult your healthcare provider to ensure the information displayed on this page applies to your...
Conclusion: Hyperglycemia accentuated hypoglycemia- induced neuronal injury, likely via PARP-1 overactivation. Although BDNF was upregulated, it was not neuroprotective and potentially exaggerated injury by binding to p75NTR recep- tor. Conversely, ketonemia during hypoglycemia attenuated neuronal injury. ...
Hyper- and hypoglycemia Most loop and thiazide diuretics are associated with insulin resistance and a dose-related increase in incident diabetes risk [70]. Hyperglycemia theoretically contributes to fall risk because of osmotic diuresis leading to dehydration and neurocognitive symptoms. Insulin resistance ...
Moreover, increased AA in aldh2.1−/− zebrafish did not induce hyperglycemia, instead AA inhibited the expression of glucokinase (gck) and glucose-6-phosphatase (g6pc), which led to an impaired glucose metabolism. In conclusion, the data have identified AA as the preferred substrate for ...
We observed changes of gut microbiota composition and derived microbial compounds by interventions of polysaccharide from Dendrobium officinale leaves in T2D mice, and its action mechanism in relation to insulin resistance and hypoglycemia in diabetic rats. Dendrobium officinale leaves polysaccharides have bee...
Cryer PE. The barrier of hypoglycemia in diabetes. Diabetes. 2008;57(12):3169-317619033403PubMedGoogle ScholarCrossref 14. Cryer PE. Management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes...
induce β-cells failure and hyperglycemia to finally increase BC cell growth [63]. Hyperglycemia increases the production of free radicals, damage and mutations in oncogenes and tumor suppressor genes and finally proliferation of cancer cells [67]. In addition, obesity and diabetes increase BC cell...
Occurrences of hypoglycemia and hyperglycemia did not differ between groups (eTable 3 in Supplement 2). Discussion Findings of this randomized clinical trial show that 8-hour TRE produced greater weight loss when compared with CR and a control condition. Despite the greater weight loss achieved by...