Crysis#3Official summary: "The mysteries of Lingshan deepen as Prophet and the remnants of Raptor Team race to reach an extraction point on the far aside of the island. Their only route of escape-through the mountain stronghold of the alien creatures. What they find waiting for them there wi...
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We are collecting HbA1C blood samples - an indicator of long-term glucose control as two-panel measurements in the hottest months of 2021 and 2022, respectively, using the HemoCue® HbA1c 501 System. A qualified phlebotomist took 4 ml of whole blood by venipuncture for each participant. ...
project, led the recruitment of the participants and sample acquisition for the study, performed statistical analysis, contributed to the interpretation of results and participated in the primary drafting of the manuscript. All other authors contributed genotypes of control samples or summary statistics ...
Human to vector transmission of malaria requires that some blood-stage parasites abandon asexual growth and convert into non-replicating sexual forms called gametocytes. The initial steps of gametocytogenesis remain largely uncharacterized. Here, we study this part of the malaria life cycle in Plasmodi...
Summary Tumors exhibit altered metabolism compared to normal tissues. Many cancers upregulate expression of serine synthesis pathway enzymes, and some tumors exhibit copy-number gain of the gene encoding the first enzyme in the pathway, phosphoglycerate dehydrogenase (PHGDH). However, whether increased se...
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As suggested by the GSEA guideline, a false discovery rate < 25% was used as the threshold to select significant enrichment. Reporting summary Further information on research design is available in the Nature Research Reporting Summary linked to this article....
SGS features multi-organ involvement with severe intellectual and physical deficits due, at least in part, to early neurodegeneration. Here we introduce a human SGS model that displays disease-relevant phenotypes. We show that SGS neural progenitors exhibit aberrant proliferation, deregulation of ...