“sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, avoiding immune destruction, cancer-promoting inflammation, genome instability and mutation, and deregulating cellular energetics” [4]...
Kim, Kang-Rae, Mu-Sung Sung, Yujin Hwang, Ju Hui Jeong, and Jeong-Nam Yu. 2024. "Assessment of the Genetic Diversity and Structure of the Korean Endemic Freshwater Fish Microphysogobio longidorsalis (Gobioninae) Using Microsatellite Markers: A First Glance from Population Genetics" Genes 15...
A genome-wide analysis using chromatin immunoprecipitation followed by next-generation sequencing (ChIP-seq) showed that the H3K27me3 level is significantly increased at the SVP locus in brm mutants compared to wild-type [105]. In addition, the SVP transcript is decreased in the brm mutant, ...
Kawano, N.; Ichinose, K.; Ebizuka, Y. Molecular cloning and functional expression of cDNAs encoding oxidosqualene cyclases from Costus speciosus.Biol. Pharm. Bull.2002,25, 477–482. [Google Scholar] [CrossRef] Herrera, J.B.; Bartel, B.; Wilson, W.K.; Matsuda, S.P. Cloning and char...
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In addition, advanced genome-editing technology, such as the CRISPR/Cas9 system and base editing technique, could be further applied to correct these harmful polymorphic sites and evaluate their clinical significances in further research.Author Contributions Conceptualization, Q.S. and Y.S.; ...
Cardiovascular diseases are a major health problem, and long-term survival for people diagnosed with heart failure is, still, unrealistic. Pathological cardiac hypertrophy largely contributes to morbidity and mortality, as effective therapeutic approache
Figure 3.Effect of SPD on AAA progression and gut microbiota modulation. (A) Detailed schematics for the experimental AAA models used in this study. (B,C) The growth rate of abdominal aortic intra-diameter and extra-diameter, respectively, for the experimental AAA models of PPE group (n = ...
Comparative Genome Analysis Reveals the Molecular Basis of Niche Adaptation of Staphylococcus epidermidis Strains. Front. Genet. 2020, 11, 566080. [Google Scholar] [CrossRef] [PubMed] Méric, G.; Mageiros, L.; Pensar, J.; Laabei, M.; Yahara, K.; Pascoe, B.; Kittiwan, N.; Tadee, ...
Although sensibility limitations would exist and the infection can be underestimated, comparative genome and transcriptome analysis have determined that the peptides belonging to CFP-10, ESAT-6 and RV3615c antigens, when used simultaneously, attain a similar or even better performance than the ...