There are a series of crucial steps in achieving dental pulp regeneration and forming a physiological pulpodentinal complex, for instance, differentiation from MSCs to functional dental pulp cells (DPCs), the promotion of angiogenesis, and the facilitation of neural reconstruction.153 Such as stem ce...
Ultrasound is a very useful tool in both diagnostic and interventional procedures in sports events. Ultrasound can provide a quick evaluation of a particular area affected during a sports injury which would then help the sports physician decide on what t
Elastin-like polypeptides (ELPs) are thermally responsive biopolymers derived from natural elastin. These peptides have a low critical solution temperature phase behavior and can be used to prepare stimuli-responsive biomaterials. Through genetic engineering, biomaterials prepared from ELPs can have unique...
3b and d). Therefore, we performed a series of rescue experiments using osm-6 genomic DNA in the osm-6(p811) mutants to identify the candidate water-sensing cells. The extrachromosomal expression of osm-6 DNA driven by its own promoter or that of tax-2 fully rescued the hydropreference ...
The advent of modern antibiotics contributed enormously to the dramatic extension of human lifespan since their discovery by virtue of their lethal and selective action against pathogenic microbes. And yet despite our powerful arsenal of weapons against
Therefore, it is important to assess the advantages of such approaches against more basic improvement or A&F strategies with fewer data demands. Conducting head-to-head experiments informed by current empirical and theoretical insights in A&F research is also a global priority [21, 41]. Head-to-...
the binding capacity of ranibi- zumab 30 days after injection.68 However, it is important to remember that these values were derived from experimental studies involving nonprimate animals (mainly rabbits) and so the results could be different if the experiments were per- formed...
To further explore these bioinformatics findings, we performed proteomic analysis of cisplatin-treated ovarian cancer cells. Finally, we demonstrated that the splicing inhibitor pladienolide B impairs the cellular response to DNA damage and significantly increases the sensitivity of cancer cells to ...
Neovascular age-related macular degeneration (nAMD) is a major cause of visual impairment and blindness. Anti-vascular endothelial growth factor (VEGF) agents, such as ranibizumab, bevacizumab, aflibercept, brolucizumab and faricimab have revolutionized
evolutionary rate remains to be seen as no critical phenotypic changes were observed in our animal models using white-tailed deer origin viruses. Still, SARS-CoV-2 has transmitted in white-tailed deer populations for a relatively short duration, and the risk of future changes may have serious ...