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T1082 Important Role of Plasma Membrane Ca2+ Channels and Ca2+ Signaling in Acid-Stimulated Duodenal Mucosal Bicarbonate Secretion - Gastroenterologydoi:10.1016/S0016-5085(08)62243-XKo, Kwang HyunDong, XiaoLee, JonathanDong, HuiElsevier Inc.Gastroenterology...
Here, we have investigated the effects of membrane localisation of PDK-1 on PKB activation. RESULTS: Ectopically expressed PDK-1 translocated to the plasma membrane in response to platelet-derived growth factor (PDGF) and translocation was sensitive to wortmannin, an inhibitor of phosphoinositide 3-...
To identify the components of the inclusions, green fluorescent protein (GFP) was fused to the carboxy-terminus (C-terminus) of SVBV open reading frames, these constructs were separately transformed into Agrobacterium tumefaciens and infiltrated into Nicotiana benthamiana leaves. Results showed that the...
Lipids are vital structural and functional components of the brain, comprising approximately 50% of its dry weight. In gliomas, abnormal lipid metabolism is intricately linked to the disease’s development and progression. This includes the reprogramming of lipid biosynthesis pathways, the involvement of...
Successful development of Plasmodium sexual stages is essential for parasite survival, but the genes involved are poorly understood. We 'knocked out' the male development gene-1 ( mdv-1) locus in Plasmodium berghei and found it to be important in female gametocyte activation. Indirect immunofluor...
We consider the plasma membrane that contains a cholesterol molar fraction of 0.4 and ask how that cholesterol is distributed between the two leaves. Because of the rapid flip-flop of cholesterol between leaves, we assume that its distribution is determined by the equality of its chemical potential...
Normal and malignant cells shed from their surface membranes as well as secrete from the endosomal membrane compartment circular membrane fragments called microvesicles (MV). MV that are released from viable cells are usually smaller in size compared to
in the existence of large electrochemical gradients across the plasma membrane as well as membranes of other subcellular compartments such as vacuole and endoplasmic reticulum (Stael et al.2012). Different stimuli can induce the gating of Ca2+-permeable channels thus allowing Ca2+to enter into the...