NMR spectroscopyrelaxationdynamicsentropyallosteryequilibriamolecular recognitionDynamic motions in proteins facilitate many biochemical phenomena, for example, catalysis and allostery. Nuclear Magnetic Resonance (NMR) spectroscopy allows measurement of protein dynamics over a wide range of timescales....
Establishment of an analytical method for accurate purity evaluations of acylcarnitines by using quantitative H-1 NMR spectroscopy Recently, it has become possible to examine metabolism abnormalities by detecting increases in specific acylcarnitines in blood tests of newborn babies usi... YIT Saito - ...
where Nc7G is N-cycloheptylglycine) and B-10284 (Arg1-Pro2-Pro3-Gly4-Phe5-Thr6-DTic7-Oic8-NH2; where Tic is 1,2,3,4-tetrahy- droisoquinoline-3-carboxylic acid), were studied in detail by NMR spectroscopy in 60% CD3OH/40% H2O and modeled by a simulated annealing protocol to de...
Nonmicellar systems for solution NMR spectroscopy of membrane proteins. Curr. Opin. Struct. Biol. 20, 471–479 (2010). Article CAS PubMed PubMed Central Google Scholar Download references Acknowledgements We thank all members of the Robinson group for helpful discussions and the many collaborators...
3-propanediammonium, 1,4- bn H 2 = 1,4-butanediammonium, and mipa H = monoisopropylammonium) were synthesized by the base promoted cation exchange reaction and characterized by elemental analysis, infrared, Raman , UV-Vis and 1 H NMR spectroscopy as well as single crystal X-ray ...
where Nc7G is N-cycloheptylglycine) and B-10284 (Arg1-Pro2-Pro3-Gly4-Phe5-Thr6-DTic7-Oic8-NH2; where Tic is 1,2,3,4-tetrahy- droisoquinoline-3-carboxylic acid), were studied in detail by NMR spectroscopy in 60% CD3OH/40% H2O and modeled by a simulated annealing protocol to de...
differential cross-polarization magic angle spinning (CP/MAS and DCP/MAS) solid-state NMR spectroscopy studies of native bone and of the isolated crystals of the calcified matrix synthesized by osteoblasts in cell culture identified and characterized the major PO4-3 phosphate components of the ...
However, determining the structure of a given protein is often very challenging. Traditional techniques like x-ray crystallography, NMR spectroscopy or cryo-electron microscopy, which can lead to high-resolution structures, cannot always be used or require a large amount of experimental effort (1, ...
The strengths and weaknesses of NMR spectroscopy and mass spectrometry with particular focus on metabolomics research. Methods Mol. Biol. 1277, 161–193 (2015). Article CAS PubMed Google Scholar Nagy, B. et al. Follicular fluid progesterone concentration is associated with fertilization outcome ...
Since HIV-1 fusion inhibitor peptides need to be embedded in the membrane to properly interact with their viral target, the structural features were determined by NMR spectroscopy in micelles and solved by using restrained molecular dynamics calculations. Both parent and retro-enantio peptides ...