However, the annulus is not lost in this case, but present at an abnormal location in the principal piece. These two proteins were found to function as a complex in the compartmentalization of the sperm flagellum. Moreover, this complex was found to be essential for controlling the precise ...
With human neuropeptide Y Y 2 receptor expressed in the Chinese hamster ovary (CHO) cells, the Asp 35Ala mutation, and especially the change of Pro 34Asp 35 to Ala 34Ala 35, decrease the compartmentalization and strongly accelerate internalization of the receptor. These changes are not ...
Overview of cholesterol homeostasis pathways utilized in cancer. Cells obtain cholesterol by taking it up from the extracellular environment or byde novosynthesis. Excess intracellular cholesterol can be transported out of cells with specific efflux mechanisms including ATP-binding cassette (ABC) transporter...
A subpopulation of both wild type and U(VI) reduction-impaired cells, 24–30%, accumulated amorphous uranium in the periplasm. Comparison of uranium-accumulating cells demonstrated a similar amount of periplasmic uranium accumulation in U(VI) reduction-impaired and wild type G. sulfurreducens. ...
Despite their importance, accumulation of these cations in cells can be cytotoxic2. Therefore, maintenance of metal cation homeostasis is crucial for cell function2. The cation diffusion facilitator (CDF) protein family, a conserved family of transmembrane transporters found in all domains of life, ...
This unique distribution is likely related with operational compartmentalization of plant lipid metabolism. In this review, we summarize the different mechanisms involved in homeostasis of PC in plant cells. The specific origin of chloroplast PC is examined and the involvement of the P4-ATPase family ...
However, this simple relationship is complicated by the paradox that L-arginine concentrations in endothelial cells remain sufficiently high to support NO synthesis. One mechanism proposed to explain this is compartmentalization of intracellular L-arginine into distinct, poorly interchangeable pools. In the...
Proteases are produced and released in the mucosal cells of the respiratory tract and have important physiological functions, for example, maintaining airway humidification to allow proper gas exchange. The infectious mechanism of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which...
Compartmentalization of neuronal and peripheral serotonin synthesis in Drosophila melanogaster. Genes Brain Behav. 2007, 6, 756–769. [Google Scholar] [CrossRef] Kalb, D.; Heinekamp, T.; Schieferdecker, S.; Nett, M.; Brakhage, A.A.; Hoffmeister, D. An iterative O-methyltransferase ...