Breast cancerImaging studiesIndicationsClinical interpretationSpecificationsIn the last few years formidable progress has been made in the field of breast imaging, the leading malignancy in women. Clinicians find it difficult to keep pace with the new techniques, the specifications and indications of each...
The concept of cancer stem cells responsible for tumour origin, maintenance, and resistance to treatment has gained prominence in the field of breast cancer research. The therapeutic targeting of these cells has the potential to eliminate residual disease and may become an important component of a m...
Breast cancer is a heterogeneous disease commonly categorized into three distinct therapeutic groups based on the expression of estrogen receptor alpha (ER/ESR1), progesterone receptor (PR) and the epidermal growth factor receptor HER2/ERBB2.1Metastasis to other organs, not cancer of the breast itself...
metastatic potential and resistance to chemo-and radiation-therapy.So it is necessary to effectively target CSCs in cancer therapy.This paper reviews the links of breast CSCs(BCSCs) with cancer metastasis and chemo-and radio-resistance,also discusses the potential application of BCSCs-targeted ...
Testing for germline BRCA1/2 mutations has an established predictive role in breast cancer risk assessment. More recently, studies have also identified BRCA1/2 status as clinically relevant in the selection of therapy for patients already diagnosed with
The author reflects on the paper of Banys and colleagues regarding breast cancer dormancy. He mentions that the authors on the paper reported poor prognosis in cases where metastasis of breast cancer occurred in bone marrow, saying that it is unclear that breast cancer cells show tropism for an...
Dr Sardesai on Lasofoxifene Plus Abemaciclib in ESR1-Mutant, ER+/HER2– Breast Cancer Dr Emadi on Initial Responses With Venetoclax Plus PegC in R/R AML Dr Baker on the EMBRACE Trial of the Dxcover Liquid Biopsy in Brain Cancer Dr Ahluwalia on the SURVIVE Trial of ...
Background In the developed countries, breast cancer is the most commonly diagnosed malignancy in women and the global incidence of breast cancer is still increasing worldwide. Breast cancers can be detected during breast cancer screening program which offers the best chance to treat the disease at...
In breast cancer, local IGF-1 production is mediated by surrounding stromal cells [134]. In addition to possessing the type I IGF-1R, through which the effects of IGF-1 are mediated, MCF-7 cells also produce and secrete IGF-1 binding proteins, which modulate the actions of IGF-1 and ...
Long-term risk of breast cancer in women with fibroadenoma. BACKGROUND: Fibroadenomas are benign breast tumors that are commonly diagnosed in young women and are associated with a slight increase in the risk of brea... WD Dupont,DL Page,FF Parl,... - 《N Engl J Med》 被引量: 1073发表...