Testosterone supplementation is commonly used for its effects on sexual function, bone health and body composition, yet its effects on disease outcomes are unknown. To better understand this, we identified genetic determinants of testosterone levels and
The decreased numbers of T cells in male mice may be due to the higher levels of testosterone, since this hormone may increase T cell apoptosis [22]. Our result is in line with the finding of Giron-Gonzalez et al. (2000), who found an increased peripheral Th1/Th2 cell cytokine profile...
Adolescence is a time of increased responsiveness to sex and stress hormones, during which the maturing dopaminergic neural circuitry is profoundly influenced by these factors. Testosterone, estrogen, and glucocorticoids interact with each other and have distinct, brain region-specific impacts on dopamine...
The decreased numbers of T cells in male mice may be due to the higher levels of testosterone, since this hormone may increase T cell apoptosis [22]. Our result is in line with the finding of Giron-Gonzalez et al. (2000), who found an increased peripheral Th1/Th2 cell cytokine profile...
Organizational effects of testosterone during a critical period of neonatal life have major irreversible effects on adult sexual behavior. We have investig... JV Seale,SA Wood,HC Atkinson,... - 《Endocrinology》 被引量: 170发表: 2005年 Fetal exposure to bisphenol A as a risk factor for the ...
96-Hour laboratory exposures to bifenthrin (1 ng/L to 10 ug/L) showed no changes in plasma levels of the estrogenic biomarker, vitellogenin (VTG) protein, nor changes of the sex steroids testosterone (T), 11-ketotestosterone (11-KT), and 17beta-estradiol (E2) levels in two salmonid ...
Exposure to very low levels of TBT (0.5–3 ng l−1) or a body burden of only 10–20 ng TBT/g wet tissue has been shown to cause a significant disruption in sex hormone metabolism/testosterone level, which subsequently leads to malformation of oviducts and suppression of oogenesis in ...
After the entry of testosterone in the cell by traveling freely through the bilayer membrane, this steroid is converted into dihydrotestosterone (DHT), the most potent androgen in the prostate. When DHT binds to AR, this induces a conformational change which removes the HSP attached to the ...
reflecting a sports-specific response to training, but also the effect of testosterone production during the onset of puberty [64]. The resting heart rate (HR) remained on the same level and dynamic back strength increased over the two years until it plateaued during the last half-year in the...
Omentin-1 inhibits the development of benign prostatic hyperplasia by attenuating local inflammation Article Open access 22 March 2024 Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia Article Open access 31 December...