For PI-RADS 3 lesions, none of the evaluated clinical parameters had a significant impact on the detection rate of csPCa. In conclusion, we show that enlarged prostate volume represents a major limitation in the daily practice of mpMRI-targeted biopsy. This study is t...
Dysregulated androgen receptor (AR) activity is central to various diseases, particularly prostate cancer (PCa), in which it drives tumour initiation and progression. Consequently, antagonising AR activity via anti-androgens is an indispensable treatment
Why do you think the the development of cancer can be seen as a failure of the immune system? Why are the testes located outside the body? Many aging men have enlarged prostate glands. What would be the consequence? Explain why the structure of...
Whilst anenlarged prostate(benign prostatic hyperplasia or BPH) does not necessarily cause ED, some medications used to treat BPH can. Some prostate cancer medications also haveerectile dysfunction as a side effect. Flutamide and leuprolide are examples of such medications. Can bipolar or anxiety medi...
Men with libido problems could have Parkinson’s disease (the risk of this disease is higher in men than women), be undergoing treatment for prostate cancer or an enlarged prostate, or have low testosterone. There is some good news if you elect to part ways, for whatever reason: Read “...
摘要: Background We aimed to compare the impact of systematic uncertainties in patient setup and prostate motion on three different external-beam radiotherapy protocols for prostate cancer.关键词:Systematic uncertainties Dynamic arc 3D CRT IMRT Prostate cancer ...
The real advantage of PET lies in the high positive predictive value of significantly increased uptake in non-enlarged nodes. Although new MRI sequences and the use of lymphatic contrast agents (for example, USPIO) may increase the sensitivity for nodal disease, these remain under investigation ...
However, the pool of proteins secreted in response to oncogenes is complex, and some components are actually tumor-promoting. For example, it has been reported that the secreted protein Trefoil factor 1 (TFF1) allows human prostate epithelial cells to escape OIS caused by activation of the Ras...
(SUVmax 5, arrow) coupled with an enlarged axillary node (SUVmax 9, arrow); (b) lower row: from left to right, whole body PET, axial and coronal images after 2 cycles of NAC depicting a reduction in tracer uptake in the right breast (SUVmax 2.7, arrow), in spite of an increased...
Locoregional progression was defined as cases in which the primary tumor and regional enlarged lymph nodes evaluated as PD after CRT or recurrence after CR. Distant progression was defined as a failure control of the distant metastatic lymph nodes and/or a new distant metastasis occurred. ...