INTRODUCTION :Despite a marked reduction in new cases of liver cirrhosis caused by hepatitis C virus (HCV) infection, over 500,000 new cirrhosis cases in this category were estimated globally in 2019. This contribution quantifies the relationship between alcohol use and the progression of liver ...
Introduction:A great number of different13C-labelled substrates have been evaluated to explore the harmful effects of alcohol consumption on specific hepatic functions. After degradation of the13C-tracers, the resulting13CO2exhaled in breath reflects the detoxification capacity of the liver. The aim of...
The review mainly discusses the impact of alcohol on the drug metabolism and alcohol-drug pharmacokinetic interactions. Many drugs can interact with alcohol, thereby altering the metabolism or effects of alcohol on the drugs. Drugs may affect the pharmacokinetics of alcohol by altering gastric emptying...
A robust documentation on the negative impact of binge drinking on students’ quality of life using a specific to alcohol instrument, such as the AQoLS, was needed. In particular, it seemed critical to clarify the differential effects of binge-drinking intensity and frequency, in order to ...
Alcohol has harmful effects on almost every organ system in the body, producing cardiovascular disorders, liver disease, neuropathological illness and fetal injury. The etiologic mechanisms for these effects of alcohol is a research area of considerable importance to the National Institute for Alcohol...
NAFLD is characterized by the accumulation of hepatic triglycerides (steatosis) in patients without significant alcohol consumption or viral hepatitis8. Some patients have an additional inflammatory infiltration (nonalcoholic steatohepatitis (NASH)) and can eventually develop liver fibrosis leading to an incr...
Heavy drinking is associated with various forms of alcoholic liver disease, such as cirrhosis. (People with alcohol dependence die from cirrhosis at a much higher rate than is found in the general population.) Alcohol dependence also increases the risk of injury, possibly due to alcohol-related ...
, to which smoking substantially contributed. The simultaneous reduction of smoking is therefore important for reducing the effect of alcohol on cancer risk. Main In Japan, both alcohol consumption and the proportion of heavy drinkers have been increasing for decades (The Editorial Board of the ...
BACKGROUND: It is well established that alcohol use and chronic viral hepatitis negatively affect the peripheral platelet count. However, less is known about the effects of non-alcoholic fatty liver disease (NAFLD) on the peripheral platelet count. Platelets are anucleate cells made in the bone ma...
This study aimed to provide a better understanding of the impact of paclitaxel chemotherapy on breath alcohol in an Irish population. Patients attending th