A large number of clinical trials have been conducted in lung cancer, but very few surveys have attempted to assess their impact on actual clinical practice. A questionnaire was therefore designed to address this question, and, in addition, to collect information on the numbers of patients ...
lung cancer evolution and address the primary study endpoint: determining the relationship between intratumour heterogeneity and clinical outcome. In lung adenocarcinoma, mutations in 22 out of 40 common cancer genes were under significant subclonal selection, including classical tumour initiators such as...
Impact of clinical and pathological variables on stage I non-small cell lung cancer outcomes 喜欢 0 阅读量: 17 作者:MC Lee,DC Stefanov,MB Angert,EC Cohn,N Seetharamu 摘要: e21071 Background: Stage I patients (pts) have 5-year survival ranging 50-75% suggesting heterogeneity within. ...
One of the most promising clinical research studies, available through our cancer centers, is Molecularly Informed Lung Cancer Treatment in a Community Cancer Network: A Pragmatic Consortium, calledMYLUNGfor short. The study aims to understand metastatic non-small cell lung cancer at the molecular le...
Translational lung cancer research explores issues in Oncology which can be linked to other research areas like Clinical trial, Epidermal growth factor receptor, Targeted therapy, Lung and Biomarker (medicine). In it, Progression-free survival, Adverse effect, Lymph node, KRAS and Proportional hazards...
Precision medicine is an important factor in modern oncology, and medical imaging plays an important role [1, 2]. Radiologists have extracted clinically meaningful information related to screening, diagnosis, and treatment planning for various cancer types. Traditionally, a few imaging features specific...
Journal of experimental & clinical cancer research: CR (Impact Factor: 1.5). 04/2007; 26(1):51-60 来自 ResearchGate 喜欢 0 阅读量: 16 作者: Akihito Tsuji 摘要: Background: LY2523355 is a potent allosteric inhibitor of the motor protein Eg5 which selectively inhibits bipolar mitotic spindle...
small cell lung cancer and other indications worldwide, including China. Senaparib’s preliminary clinical data demonstrated superior tolerability and wider therapeutic window compared with other PARPi. Phase I study of Wee1 inhibitor (IMP7068) is conducted globally. Hedgehog pathway inhibitor (IMP5471...
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ROS1-rearranged lung cancers benefit from first-line crizotinib therapy; however, clinical and molecular factors that could affect crizotinib efficacy in ROS1-rearranged lung cancers are not yet well-elucidated. Our retrospective study aimed to compare t