The Impact of PLoS Pathogens As we approach the second anniversary of the launch of PLoS Pathogens, it is evident that the journal has rapidly established itself as an important publication in the field of pathogen–host interactions (Image 1). We attribute this suc... J Young,K Haldar - ...
Development and Factor Structure of a Brief Instrument to Assess the Impact of Community Programs on Positive Youth Development: The Rochester Evaluation o... Positive youth development is increasingly recognized as important to the health and well-being of adolescents. We describe the development of ...
The HFDs also affected the expression of cancer-related genes in the proximal colon (and other parts of the intestines) includingVnn1, a pantetheinase with roles in oxidative stress and inflammation37, andTnfsf10(tumor necrosis factor ligand superfamily, member 10) (Fig.4E). Genes specific to...
et al. The transcription factor Rbf1 is the master regulator for b-mating type controlled pathogenic development in Ustilago maydis. PLoS Pathog. 6, e1001035 (2010). Article PubMed Central CAS PubMed Google Scholar Mendoza-Mendoza, A. et al. Physical-chemical plant-derived signals induce ...
We confirmed that, after adjusting for PSI or CURB 65, A/H1N1 etiology was an independent factor for mortality. Our findings confirmed a higher mortality in influenza A/H1N1 pneumonia compared to A/H1N1(−) pneumonia.11, 13, 32 Multilobar infiltrates and hypoxemia were also independent risk ...
The state of the microbiome, the duration, route, and spectrum of antibiotic activity, other co-morbidities, diet, and post-antibiotic environment all factor into the expected acute and chronic disruption and resilience from perturbation (Fig. 1) [7, 28, 32, 43, 55, 57, 59, 74]. With ...
important role in the disease of the 1918 virus for the HA gene [50]. The high-virulence area (s) of HA has not yet been discovered. The other central factor in the 1918 outbreak is virulence. One unusual characteristic of the pandemic of 1918 was that many people have passed away of...
gondii, while 15 (3.5%) showed amplification of the Cytochrome b gene for Plasmodium spp. A risk factor analysis indicated that the prevalence of both pathogens was not confined to specific sampling sites or bird sexes (P > 0.05). District-wise analysis highlighted that...
et al. Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: a novel mechanism for the antitumor effects of type I IFNs. J. Exp. Med. 189, 1451–1460 (1999). CAS PubMed PubMed Central Google Scholar Chawla-...
Neutrophils can also influence thrombosis through the release of a number of active proteases and other agents such as matrix metalloproteinases (MMP), serine proteases (e.g., cathepsin G and elastase) and platelet-activating factor (PAF)5,11. For instance, cathepsin G and elastase are known ...