Cancer immunotherapy is a therapeutic method for the enhancement or suppression of the immune function of the body to fight and eliminate cancer cells. From: Nano Today, 2022 About this pageSet alert Also in subject areas: Agricultural and Biological Sciences Immunology and Microbiology Medicine and...
Immunotherapy, as a powerful strategy for cancer treatment, has achieved tremendous efficacy in clinical trials. Despite these advancements, there is much to do in terms of enhancing therapeutic benefits and decreasing the side effects of cancer immunotherapy. Advanced nanobiomaterials, including liposomes,...
Lung cancer is the primary cause of mortality in the United States and around the globe. Therapeutic options for lung cancer treatment include surgery, radiation therapy, chemotherapy, and targeted drug therapy. Medical management is often associated with the development of treatment resistance leading ...
The success of immunotherapy in the treatment of melanoma is expected to result in the approval and development of additional agents over the next several years. There is considerable excitement in the field for T-cell checkpoint inhibitors for cancer therapy. Programmed death 1 (PD-1) is a T...
Cancer immunotherapy is an innovative treatment for tumors today. In various experiments and clinical studies, it has been found that immunotherapy does have incomparable advantages over traditional anti-tumor therapy, which can prolong progression-free survival (PFS) and overall survival (OS). However...
“It was very scary,” she said. “I was like, ‘What did I do bad so that God could give me this punishment?’” Desperate and out of options, Ezzy had one last chance. She was enrolled in a clinical trial at Memorial Sloan Kettering Cancer Center in Manhattan for an experimental ...
mRNA vaccines have become a promising platform for cancer immunotherapy. During vaccination, naked or vehicle loaded mRNA vaccines efficiently express tumor antigens in antigen-presenting cells (APCs), facilitate APC activation and innate/adaptive immune stimulation. mRNA cancer vaccine precedes other conve...
for curative therapy. In addition, development of effective immunotherapeutic cancer strategies requires our attention to deal with both of the immunological hallmarks of cancer: “avoiding immune destruction” and “tumor-promoting inflammation”. Presently, most of the approved cancer immunotherapeutics (...
HER2, a well-studied member of the epidermal growth factor tyrosine kinase receptor family, plays an important role in breast cancer and has been a target for ADCs. T-DM1 (Kadcyla), an ADC consisting of trastuzumab (T) and a microtubule inhibitor (DM1), was the first ADC approved by the...
Immunotherapies are yielding effective treatments for several previously untreatable cancers. Still, the identification of suitable antigens specific to the tumour that can be targets for cancer vaccines and T cell therapies is a challenge. Alternative p